Entity Details

Primary name PROP1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP97458
EntryNamePROP1_MOUSE
FullNameHomeobox protein prophet of Pit-1
TaxID10090
Evidenceevidence at protein level
Length223
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesProp1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001568 blood vessel development
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008013 beta-catenin binding
GO:0008022 protein C-terminus binding
GO:0009887 animal organ morphogenesis
GO:0009953 dorsal/ventral pattern formation
GO:0016477 cell migration
GO:0021979 hypothalamus cell differentiation
GO:0021983 pituitary gland development
GO:0021984 adenohypophysis development
GO:0043066 negative regulation of apoptotic process
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048732 gland development
GO:0048850 hypophysis morphogenesis
GO:0060070 canonical Wnt signaling pathway
GO:0060126 somatotropin secreting cell differentiation
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site
IPR042412 Homeobox protein prophet of Pit-1FamilyFamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PROP1_MOUSECTNB1_MOUSEBioGRID, IntAct16678101 details