Entity Details

Primary name TRBP2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP97473
EntryNameTRBP2_MOUSE
FullNameRISC-loading complex subunit TARBP2
TaxID10090
Evidenceevidence at protein level
Length365
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesTarbp2

GO terms

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GOName
GO:0003725 double-stranded RNA binding
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0007286 spermatid development
GO:0007338 single fertilization
GO:0016442 RISC complex
GO:0016604 nuclear body
GO:0019899 enzyme binding
GO:0030422 production of siRNA involved in RNA interference
GO:0030423 targeting of mRNA for destruction involved in RNA interference
GO:0031054 pre-miRNA processing
GO:0035087 siRNA loading onto RISC involved in RNA interference
GO:0035196 production of miRNAs involved in gene silencing by miRNA
GO:0035197 siRNA binding
GO:0035198 miRNA binding
GO:0035264 multicellular organism growth
GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043403 skeletal muscle tissue regeneration
GO:0045070 positive regulation of viral genome replication
GO:0045727 positive regulation of translation
GO:0046782 regulation of viral transcription
GO:0047485 protein N-terminus binding
GO:0048471 perinuclear region of cytoplasm
GO:0050689 negative regulation of defense response to virus by host
GO:0051149 positive regulation of muscle cell differentiation
GO:0061351 neural precursor cell proliferation
GO:0070578 RISC-loading complex
GO:0070883 pre-miRNA binding
GO:0090065 regulation of production of siRNA involved in RNA interference
GO:1903798 regulation of production of miRNAs involved in gene silencing by miRNA

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR014720 Double-stranded RNA-binding domainDomainDomain
IPR028605 RISC-loading complex subunit TRBP2FamilyFamily
IPR044469 TRBP2 , first double-stranded RNA binding domainDomainDomain
IPR044470 TRBP2 , second double-stranded RNA binding domainDomainDomain
IPR044471 TRBP2 , third double-stranded RNA binding domainDomainDomain

Diseases

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