Entity Details

Primary name AURKA_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP97477
EntryNameAURKA_MOUSE
FullNameAurora kinase A
TaxID10090
Evidenceevidence at protein level
Length395
SequenceStatuscomplete
DateCreated2003-01-27
DateModified2021-06-02

Ontological Relatives

GenesAurka

GO terms

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GOName
GO:0000212 meiotic spindle organization
GO:0000226 microtubule cytoskeleton organization
GO:0000278 mitotic cell cycle
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005813 centrosome
GO:0005814 centriole
GO:0005815 microtubule organizing center
GO:0005819 spindle
GO:0005829 cytosol
GO:0005876 spindle microtubule
GO:0005929 cilium
GO:0006468 protein phosphorylation
GO:0007051 spindle organization
GO:0007052 mitotic spindle organization
GO:0007057 spindle assembly involved in female meiosis I
GO:0007098 centrosome cycle
GO:0007100 mitotic centrosome separation
GO:0009611 response to wounding
GO:0009948 anterior/posterior axis specification
GO:0010629 negative regulation of gene expression
GO:0015630 microtubule cytoskeleton
GO:0018105 peptidyl-serine phosphorylation
GO:0019901 protein kinase binding
GO:0031616 spindle pole centrosome
GO:0031625 ubiquitin protein ligase binding
GO:0031647 regulation of protein stability
GO:0032091 negative regulation of protein binding
GO:0032133 chromosome passenger complex
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032465 regulation of cytokinesis
GO:0035174 histone serine kinase activity
GO:0042585 germinal vesicle
GO:0043066 negative regulation of apoptotic process
GO:0043203 axon hillock
GO:0045120 pronucleus
GO:0046982 protein heterodimerization activity
GO:0048471 perinuclear region of cytoplasm
GO:0051233 spindle midzone
GO:0051301 cell division
GO:0051321 meiotic cell cycle
GO:0051642 centrosome localization
GO:0071539 protein localization to centrosome
GO:0072686 mitotic spindle
GO:0072687 meiotic spindle
GO:0097421 liver regeneration
GO:0097431 mitotic spindle pole
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1900195 positive regulation of oocyte maturation
GO:1990138 neuron projection extension

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR030616 Aurora kinaseFamilyFamily

Diseases

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