Entity Details

Primary name GRM1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP97772
EntryNameGRM1_MOUSE
FullNameMetabotropic glutamate receptor 1
TaxID10090
Evidenceevidence at protein level
Length1199
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesGrm1

GO terms

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GOName
GO:0000186 obsolete activation of MAPKK activity
GO:0000187 obsolete activation of MAPK activity
GO:0001639 PLC activating G protein-coupled glutamate receptor activity
GO:0001640 adenylate cyclase inhibiting G protein-coupled glutamate receptor activity
GO:0005634 nucleus
GO:0005887 integral component of plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007216 G protein-coupled glutamate receptor signaling pathway
GO:0007626 locomotory behavior
GO:0008066 glutamate receptor activity
GO:0014069 postsynaptic density
GO:0019233 sensory perception of pain
GO:0019722 calcium-mediated signaling
GO:0030331 estrogen receptor binding
GO:0030424 axon
GO:0030425 dendrite
GO:0038037 G protein-coupled receptor dimeric complex
GO:0038038 G protein-coupled receptor homodimeric complex
GO:0042734 presynaptic membrane
GO:0042802 identical protein binding
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043197 dendritic spine
GO:0043408 regulation of MAPK cascade
GO:0045211 postsynaptic membrane
GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
GO:0051930 regulation of sensory perception of pain
GO:0051966 regulation of synaptic transmission, glutamatergic
GO:0071257 cellular response to electrical stimulus
GO:0098685 Schaffer collateral - CA1 synapse
GO:0098712 L-glutamate import across plasma membrane
GO:0098839 postsynaptic density membrane
GO:0098872 G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
GO:0098978 glutamatergic synapse
GO:0099055 integral component of postsynaptic membrane
GO:0099061 integral component of postsynaptic density membrane
GO:0099530 G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential
GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000162 GPCR, family 3, metabotropic glutamate receptorFamilyFamily
IPR000337 GPCR, family 3FamilyFamily
IPR001256 GPCR, family 3, metabotropic glutamate receptor 1FamilyFamily
IPR001828 Receptor, ligand binding regionDomainDomain
IPR011500 GPCR, family 3, nine cysteines domainDomainDomain
IPR017978 GPCR family 3, C-terminalDomainDomain
IPR017979 GPCR, family 3, conserved siteSiteConserved site
IPR019588 Metabotropic glutamate receptor, Homer-binding domainDomainDomain
IPR028082 Periplasmic binding protein-like IFamilyHomologous superfamily
IPR038550 GPCR, family 3, nine cysteines domain superfamilyFamilyHomologous superfamily

Diseases

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