Entity Details

Primary name CRY1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP97784
EntryNameCRY1_MOUSE
FullNameCryptochrome-1
TaxID10090
Evidenceevidence at protein level
Length606
SequenceStatuscomplete
DateCreated2006-11-28
DateModified2021-06-02

Ontological Relatives

GenesCry1

GO terms

Show/Hide Table
GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006094 gluconeogenesis
GO:0006975 DNA damage induced protein phosphorylation
GO:0007623 circadian rhythm
GO:0008134 transcription factor binding
GO:0009416 response to light stimulus
GO:0009881 photoreceptor activity
GO:0014823 response to activity
GO:0018298 protein-chromophore linkage
GO:0019900 kinase binding
GO:0019901 protein kinase binding
GO:0019902 phosphatase binding
GO:0019915 lipid storage
GO:0031397 negative regulation of protein ubiquitination
GO:0031398 positive regulation of protein ubiquitination
GO:0032868 response to insulin
GO:0032922 circadian regulation of gene expression
GO:0033762 response to glucagon
GO:0042593 glucose homeostasis
GO:0042752 regulation of circadian rhythm
GO:0042754 negative regulation of circadian rhythm
GO:0042826 histone deacetylase binding
GO:0043153 entrainment of circadian clock by photoperiod
GO:0045721 negative regulation of gluconeogenesis
GO:0045744 negative regulation of G protein-coupled receptor signaling pathway
GO:0045892 negative regulation of transcription, DNA-templated
GO:0070888 E-box binding
GO:0071949 FAD binding
GO:2000001 regulation of DNA damage checkpoint
GO:2000323 negative regulation of glucocorticoid receptor signaling pathway
GO:2000850 negative regulation of glucocorticoid secretion

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR005101 Cryptochrome/DNA photolyase, FAD-binding domainDomainDomain
IPR006050 DNA photolyase, N-terminalDomainDomain
IPR014729 Rossmann-like alpha/beta/alpha sandwich foldFamilyHomologous superfamily
IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamilyFamilyHomologous superfamily
IPR036155 Cryptochrome/photolyase, N-terminal domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

41 interactions

InteractorPartnerSourcesPublicationsLink
CRY1_MOUSEFBXL3_MOUSEBioGRID, IntAct17462724 23452855 23452856 30655559 details
CRY1_MOUSEBMAL1_MOUSEBioGRID, DIP, IntAct14701732 15226430 16717091 16777965 18075593 18430226 20832105 21966515 23555304 24737000 25127877 25961797 26562092 details
CRY1_MOUSECLOCK_MOUSEBioGRID, DIP, IntAct14701732 16717091 16777965 18075593 18430226 18662546 23555304 25127877 25961797 details
CRY1_MOUSE2A5E_HUMANIntAct23555304 details
CRY1_MOUSEPER2_MOUSEBioGRID, DIP, IntAct, MINT14701732 21680841 22170608 23079727 23452855 23555304 24413057 24737000 24855952 25127877 details
CRY1_MOUSENPAS2_HUMANDIP, IntAct23555304 24737000 details
CRY1_MOUSEBHE41_MOUSEIntAct23555304 details
CRY1_MOUSEBHE40_HUMANIntAct23555304 details
CRY1_MOUSECSK2B_HUMANDIP, IntAct23555304 26562092 details
CRY1_MOUSE2A5D_HUMANIntAct23555304 details
CRY1_MOUSE2AAB_HUMANIntAct23555304 details
CRY1_MOUSEPER1_MOUSEBioGRID, DIP, IntAct14701732 21680841 21966515 23133559 23555304 24737000 25127877 details
CRY1_MOUSEKC1E_MOUSEBioGRID, IntAct21966515 23555304 details
CRY1_MOUSENR1D2_HUMANIntAct23555304 details
CRY1_MOUSEFXL21_MOUSEIntAct23452855 23452856 details
CRY1_MOUSECLOCK_HUMANBioGRID, DIP, IntAct24737000 26496610 details
CRY1_MOUSEIFM1_MOUSEDIP24737000 details
CRY1_MOUSECBS_MOUSEDIP24737000 details
CRY1_MOUSEPER3_MOUSEBioGRID, DIP14701732 24737000 details
CRY1_MOUSEBMAL2_MOUSEDIP25961797 details
CRY1_MOUSECSK22_HUMANDIP26562092 details
CRY1_MOUSECSK21_HUMANDIP26562092 details
CRY1_MOUSETIM_MOUSEBioGRID12875843 20211142 details
CRY1_MOUSESIN3B_MOUSEBioGRID15226430 details
CRY1_MOUSEHDAC1_MOUSEBioGRID15226430 details
CRY1_MOUSEHDAC2_MOUSEBioGRID15226430 details
CRY1_MOUSEKC1E_HUMANBioGRID, IntAct11875063 26496610 details
CRY1_MOUSEMK01_MOUSEDIP21179498 details
CRY1_MOUSEKC1A_MOUSEDIP21179498 details
CRY1_MOUSEGCR_MOUSEDIP22170608 details
CRY1_MOUSERORA_MOUSEDIP22170608 details
CRY1_MOUSEGCR_HUMANDIP22170608 details
CRY1_MOUSERORG_MOUSEDIP22170608 details
CRY1_MOUSEANDR_MOUSEDIP22170608 details
CRY1_MOUSECSK2B_MOUSEDIP26562092 details
CRY1_MOUSEANM5_MOUSEIntAct23133559 details
CRY1_MOUSEDTL_HUMANIntAct26431207 details
CRY1_MOUSECRY2_MOUSEBioGRID14701732 details
CRY1_MOUSEEZH2_MOUSEBioGRID16717091 details
CRY1_MOUSEUBP2_MOUSEBioGRID21966515 23213472 details
CRY1_MOUSETLK2_HUMANBioGRID30655559 details