Entity Details

Primary name XRN1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP97789
EntryNameXRN1_MOUSE
FullName5'-3' exoribonuclease 1
TaxID10090
Evidenceevidence at protein level
Length1719
SequenceStatuscomplete
DateCreated2005-12-20
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0000723 telomere maintenance
GO:0000932 P-body
GO:0000956 nuclear-transcribed mRNA catabolic process
GO:0002151 G-quadruplex RNA binding
GO:0003723 RNA binding
GO:0004534 5'-3' exoribonuclease activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006396 RNA processing
GO:0007569 cell aging
GO:0016075 rRNA catabolic process
GO:0017148 negative regulation of translation
GO:0030425 dendrite
GO:0043025 neuronal cell body
GO:0045202 synapse
GO:0051321 meiotic cell cycle
GO:0051880 G-quadruplex DNA binding
GO:0071028 nuclear mRNA surveillance
GO:0071044 histone mRNA catabolic process
GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR004859 Putative 5-3 exonucleaseDomainDomain
IPR016494 5'-3' exoribonuclease 1FamilyFamily
IPR027073 5'-3' exoribonucleaseFamilyFamily
IPR040992 Xrn1, D1 domainDomainDomain
IPR041385 5'-3' exoribonuclease 1, SH3-like domainDomainDomain
IPR041412 Xrn1, helical domainDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
XRN1_MOUSENANO2_MOUSEDIP20133598 details