Entity Details

Primary name ALK_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP97793
EntryNameALK_MOUSE
FullNameALK tyrosine kinase receptor
TaxID10090
Evidenceevidence at protein level
Length1621
SequenceStatuscomplete
DateCreated2002-03-27
DateModified2021-06-02

Ontological Relatives

GenesAlk

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007275 multicellular organism development
GO:0007399 nervous system development
GO:0007420 brain development
GO:0016310 phosphorylation
GO:0021766 hippocampus development
GO:0030424 axon
GO:0030534 adult behavior
GO:0032991 protein-containing complex
GO:0033674 positive regulation of kinase activity
GO:0036269 swimming behavior
GO:0042127 regulation of cell population proliferation
GO:0042802 identical protein binding
GO:0043235 receptor complex
GO:0044297 cell body
GO:0045664 regulation of neuron differentiation
GO:0046777 protein autophosphorylation
GO:0048666 neuron development
GO:0050995 negative regulation of lipid catabolic process
GO:0060159 regulation of dopamine receptor signaling pathway
GO:0090648 response to environmental enrichment
GO:0097009 energy homeostasis
GO:1900006 positive regulation of dendrite development

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR000998 MAM domainDomainDomain
IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domainDomainDomain
IPR002011 Tyrosine-protein kinase, receptor class II, conserved siteSiteConserved site
IPR002172 Low-density lipoprotein (LDL) receptor class A repeatRepeatRepeat
IPR008266 Tyrosine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR020635 Tyrosine-protein kinase, catalytic domainDomainDomain
IPR026830 ALK tyrosine kinase receptorFamilyFamily
IPR036055 LDL receptor-like superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ALK_MOUSESHC1_MOUSEBioGRID15226403 details