Entity Details

Primary name SHPS1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP97797
EntryNameSHPS1_MOUSE
FullNameTyrosine-protein phosphatase non-receptor type substrate 1
TaxID10090
Evidenceevidence at protein level
Length513
SequenceStatuscomplete
DateCreated2003-03-28
DateModified2021-06-02

Ontological Relatives

GenesSirpa

GO terms

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GOName
GO:0001933 negative regulation of protein phosphorylation
GO:0002244 hematopoietic progenitor cell differentiation
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006910 phagocytosis, recognition
GO:0006911 phagocytosis, engulfment
GO:0007010 cytoskeleton organization
GO:0007015 actin filament organization
GO:0007160 cell-matrix adhesion
GO:0009986 cell surface
GO:0010468 regulation of gene expression
GO:0016477 cell migration
GO:0017124 SH3 domain binding
GO:0019903 protein phosphatase binding
GO:0030695 GTPase regulator activity
GO:0032649 regulation of interferon-gamma production
GO:0032651 regulation of interleukin-1 beta production
GO:0032675 regulation of interleukin-6 production
GO:0032680 regulation of tumor necrosis factor production
GO:0032688 negative regulation of interferon-beta production
GO:0032715 negative regulation of interleukin-6 production
GO:0032720 negative regulation of tumor necrosis factor production
GO:0035696 monocyte extravasation
GO:0045019 negative regulation of nitric oxide biosynthetic process
GO:0045309 protein phosphorylated amino acid binding
GO:0045428 regulation of nitric oxide biosynthetic process
GO:0046329 negative regulation of JNK cascade
GO:0050728 negative regulation of inflammatory response
GO:0050765 negative regulation of phagocytosis
GO:0050766 positive regulation of phagocytosis
GO:0050870 positive regulation of T cell activation
GO:0070301 cellular response to hydrogen peroxide
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0071222 cellular response to lipopolysaccharide
GO:0071346 cellular response to interferon-gamma
GO:0071347 cellular response to interleukin-1
GO:0071349 cellular response to interleukin-12
GO:0071641 negative regulation of macrophage inflammatory protein 1 alpha production
GO:0071650 negative regulation of chemokine (C-C motif) ligand 5 production
GO:0086080 protein binding involved in heterotypic cell-cell adhesion
GO:0097530 granulocyte migration
GO:0098632 cell-cell adhesion mediator activity
GO:1900016 negative regulation of cytokine production involved in inflammatory response
GO:1903720 negative regulation of I-kappaB phosphorylation
GO:1990405 protein antigen binding
GO:1990782 protein tyrosine kinase binding

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR003006 Immunoglobulin/major histocompatibility complex, conserved siteSiteConserved site
IPR003597 Immunoglobulin C1-setDomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013106 Immunoglobulin V-set domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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