Entity Details

Primary name VLDLR_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP98156
EntryNameVLDLR_MOUSE
FullNameVery low-density lipoprotein receptor
TaxID10090
Evidenceevidence at protein level
Length873
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesVldlr

GO terms

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GOName
GO:0005509 calcium ion binding
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005905 clathrin-coated pit
GO:0006869 lipid transport
GO:0006898 receptor-mediated endocytosis
GO:0008203 cholesterol metabolic process
GO:0009986 cell surface
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0021517 ventral spinal cord development
GO:0030229 very-low-density lipoprotein particle receptor activity
GO:0034185 apolipoprotein binding
GO:0034189 very-low-density lipoprotein particle binding
GO:0034361 very-low-density lipoprotein particle
GO:0034436 glycoprotein transport
GO:0034447 very-low-density lipoprotein particle clearance
GO:0038024 cargo receptor activity
GO:0038025 reelin receptor activity
GO:0038026 reelin-mediated signaling pathway
GO:0043235 receptor complex
GO:0045177 apical part of cell
GO:0045860 positive regulation of protein kinase activity
GO:0048306 calcium-dependent protein binding
GO:0048471 perinuclear region of cytoplasm
GO:0048813 dendrite morphogenesis
GO:0071456 cellular response to hypoxia
GO:1900006 positive regulation of dendrite development

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR000033 LDLR class B repeatRepeatRepeat
IPR000152 EGF-type aspartate/asparagine hydroxylation sitePTMPTM
IPR000742 EGF-like domainDomainDomain
IPR001881 EGF-like calcium-binding domainDomainDomain
IPR002172 Low-density lipoprotein (LDL) receptor class A repeatRepeatRepeat
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR011042 Six-bladed beta-propeller, TolB-likeFamilyHomologous superfamily
IPR018097 EGF-like calcium-binding, conserved siteSiteConserved site
IPR023415 Low-density lipoprotein (LDL) receptor class A, conserved siteSiteConserved site
IPR032931 Very low-density lipoprotein receptorFamilyFamily
IPR036055 LDL receptor-like superfamilyFamilyHomologous superfamily

Diseases

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