Entity Details

Primary name TCF7_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ00417
EntryNameTCF7_MOUSE
FullNameTranscription factor 7
TaxID10090
Evidenceevidence at protein level
Length419
SequenceStatuscomplete
DateCreated1995-02-01
DateModified2021-06-02

Ontological Relatives

GenesTcf7

GO terms

Show/Hide Table
GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000791 euchromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001217 DNA-binding transcription repressor activity
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008013 beta-catenin binding
GO:0021915 neural tube development
GO:0030538 embryonic genitalia morphogenesis
GO:0033153 T cell receptor V(D)J recombination
GO:0042127 regulation of cell population proliferation
GO:0042492 gamma-delta T cell differentiation
GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process
GO:0045586 regulation of gamma-delta T cell differentiation
GO:0046632 alpha-beta T cell differentiation
GO:0048557 embryonic digestive tract morphogenesis
GO:0048619 embryonic hindgut morphogenesis
GO:0060070 canonical Wnt signaling pathway
GO:1990907 beta-catenin-TCF complex

Subcellular Location

Show/Hide Table
Subcellular Location
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR009071 High mobility group box domainDomainDomain
IPR013558 CTNNB1 binding, N-teminalDomainDomain
IPR024940 Transcription factor TCF/LEFFamilyFamily
IPR027397 Catenin binding domain superfamilyFamilyHomologous superfamily
IPR028785 Transcription factor 7FamilyFamily
IPR036910 High mobility group box domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
TCF7_MOUSEDACT2_MOUSEUniProt21718540 details
TCF7_MOUSELEF1_MOUSEBioGRID24748645 details