Entity Details

Primary name IL6RB_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ00560
EntryNameIL6RB_MOUSE
FullNameInterleukin-6 receptor subunit beta
TaxID10090
Evidenceevidence at protein level
Length917
SequenceStatuscomplete
DateCreated1995-02-01
DateModified2021-06-02

Ontological Relatives

GenesIl6st

GO terms

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GOName
GO:0004896 cytokine receptor activity
GO:0004897 ciliary neurotrophic factor receptor activity
GO:0004915 interleukin-6 receptor activity
GO:0004923 leukemia inhibitory factor receptor activity
GO:0004924 oncostatin-M receptor activity
GO:0005127 ciliary neurotrophic factor receptor binding
GO:0005138 interleukin-6 receptor binding
GO:0005615 extracellular space
GO:0005896 interleukin-6 receptor complex
GO:0005900 oncostatin-M receptor complex
GO:0005977 glycogen metabolic process
GO:0006642 triglyceride mobilization
GO:0007165 signal transduction
GO:0008284 positive regulation of cell population proliferation
GO:0008593 regulation of Notch signaling pathway
GO:0009897 external side of plasma membrane
GO:0014911 positive regulation of smooth muscle cell migration
GO:0019221 cytokine-mediated signaling pathway
GO:0019838 growth factor binding
GO:0019955 cytokine binding
GO:0019981 interleukin-6 binding
GO:0030425 dendrite
GO:0032809 neuronal cell body membrane
GO:0034097 response to cytokine
GO:0038154 interleukin-11-mediated signaling pathway
GO:0038165 oncostatin-M-mediated signaling pathway
GO:0042102 positive regulation of T cell proliferation
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0042802 identical protein binding
GO:0043025 neuronal cell body
GO:0043235 receptor complex
GO:0044297 cell body
GO:0045669 positive regulation of osteoblast differentiation
GO:0045747 positive regulation of Notch signaling pathway
GO:0048711 positive regulation of astrocyte differentiation
GO:0048861 leukemia inhibitory factor signaling pathway
GO:0051481 negative regulation of cytosolic calcium ion concentration
GO:0060576 intestinal epithelial cell development
GO:0070102 interleukin-6-mediated signaling pathway
GO:0070104 negative regulation of interleukin-6-mediated signaling pathway
GO:0070106 interleukin-27-mediated signaling pathway
GO:0070110 ciliary neurotrophic factor receptor complex
GO:0070120 ciliary neurotrophic factor-mediated signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR003529 Long hematopoietin receptor, Gp130 family 2, conserved siteSiteConserved site
IPR003961 Fibronectin type IIIDomainDomain
IPR010457 Immunoglobulin C2-set-like, ligand-bindingDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR015321 Type I cytokine receptor, cytokine-binding domainDomainDomain
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily

Diseases

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