Entity Details

Primary name CD80_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ00609
EntryNameCD80_MOUSE
FullNameT-lymphocyte activation antigen CD80
TaxID10090
Evidenceevidence at protein level
Length306
SequenceStatuscomplete
DateCreated1994-02-01
DateModified2021-06-02

Ontological Relatives

GenesCd80

GO terms

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GOName
GO:0006955 immune response
GO:0007166 cell surface receptor signaling pathway
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0015026 coreceptor activity
GO:0016021 integral component of membrane
GO:0031295 T cell costimulation
GO:0042102 positive regulation of T cell proliferation
GO:0042130 negative regulation of T cell proliferation
GO:0046641 positive regulation of alpha-beta T cell proliferation
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0071222 cellular response to lipopolysaccharide
GO:0098636 protein complex involved in cell adhesion

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013106 Immunoglobulin V-set domainDomainDomain
IPR013162 CD80-like, immunoglobulin C2-setDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily
IPR037676 CD80, IgC-like domainDomainDomain
IPR042711 CD80, immunoglobulin variable domainDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
CD80_MOUSEPD1L1_MOUSEDIP, IntAct, Molecular Connections21884581 23417675 31000591 details
CD80_MOUSECD80_MOUSEMolecular Connections21884581 details