Entity Details

Primary name CREB1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ01147
EntryNameCREB1_MOUSE
FullNameCyclic AMP-responsive element-binding protein 1
TaxID10090
Evidenceevidence at protein level
Length327
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesCreb1

GO terms

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GOName
GO:0000785 chromatin
GO:0000791 euchromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001666 response to hypoxia
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006366 transcription by RNA polymerase II
GO:0006468 protein phosphorylation
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007409 axonogenesis
GO:0007568 aging
GO:0007595 lactation
GO:0007613 memory
GO:0007623 circadian rhythm
GO:0008134 transcription factor binding
GO:0008361 regulation of cell size
GO:0008542 visual learning
GO:0010033 response to organic substance
GO:0010629 negative regulation of gene expression
GO:0010944 negative regulation of transcription by competitive promoter binding
GO:0014823 response to activity
GO:0019899 enzyme binding
GO:0021983 pituitary gland development
GO:0030424 axon
GO:0030544 Hsp70 protein binding
GO:0030879 mammary gland development
GO:0032916 positive regulation of transforming growth factor beta3 production
GO:0033363 secretory granule organization
GO:0033762 response to glucagon
GO:0034670 chemotaxis to arachidonic acid
GO:0035035 histone acetyltransferase binding
GO:0035094 response to nicotine
GO:0035497 cAMP response element binding
GO:0035729 cellular response to hepatocyte growth factor stimulus
GO:0036120 cellular response to platelet-derived growth factor stimulus
GO:0040018 positive regulation of multicellular organism growth
GO:0042493 response to drug
GO:0042752 regulation of circadian rhythm
GO:0042802 identical protein binding
GO:0042981 regulation of apoptotic process
GO:0043065 positive regulation of apoptotic process
GO:0043565 sequence-specific DNA binding
GO:0045600 positive regulation of fat cell differentiation
GO:0045672 positive regulation of osteoclast differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045899 positive regulation of RNA polymerase II transcription preinitiation complex assembly
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046887 positive regulation of hormone secretion
GO:0046889 positive regulation of lipid biosynthetic process
GO:0048145 regulation of fibroblast proliferation
GO:0050821 protein stabilization
GO:0055025 positive regulation of cardiac muscle tissue development
GO:0060251 regulation of glial cell proliferation
GO:0060428 lung epithelium development
GO:0060430 lung saccule development
GO:0060509 type I pneumocyte differentiation
GO:0071294 cellular response to zinc ion
GO:0071300 cellular response to retinoic acid
GO:0071363 cellular response to growth factor stimulus
GO:0071398 cellular response to fatty acid
GO:1900273 positive regulation of long-term synaptic potentiation
GO:1901215 negative regulation of neuron death
GO:1902065 response to L-glutamate
GO:1990090 cellular response to nerve growth factor stimulus
GO:1990314 cellular response to insulin-like growth factor stimulus
GO:1990589 ATF4-CREB1 transcription factor complex
GO:1990763 arrestin family protein binding
GO:1990830 cellular response to leukemia inhibitory factor
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001630 cAMP response element binding (CREB) proteinFamilyFamily
IPR003102 Coactivator CBP, pKIDDomainDomain
IPR004827 Basic-leucine zipper domainDomainDomain
IPR029802 cAMP-responsive element-binding protein 1FamilyFamily

Diseases

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