Entity Details

Primary name CXA5_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ01231
EntryNameCXA5_MOUSE
FullNameGap junction alpha-5 protein
TaxID10090
Evidenceevidence at transcript level
Length358
SequenceStatuscomplete
DateCreated1993-04-01
DateModified2021-06-02

Ontological Relatives

GenesGja5

GO terms

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GOName
GO:0001501 skeletal system development
GO:0001568 blood vessel development
GO:0003071 renal system process involved in regulation of systemic arterial blood pressure
GO:0003073 regulation of systemic arterial blood pressure
GO:0003105 negative regulation of glomerular filtration
GO:0003151 outflow tract morphogenesis
GO:0003161 cardiac conduction system development
GO:0003174 mitral valve development
GO:0003193 pulmonary valve formation
GO:0003281 ventricular septum development
GO:0003283 atrial septum development
GO:0003284 septum primum development
GO:0003294 atrial ventricular junction remodeling
GO:0005243 gap junction channel activity
GO:0005887 integral component of plasma membrane
GO:0005921 gap junction
GO:0005922 connexin complex
GO:0006813 potassium ion transport
GO:0007267 cell-cell signaling
GO:0010643 cell communication by chemical coupling
GO:0010644 cell communication by electrical coupling
GO:0010649 regulation of cell communication by electrical coupling
GO:0010652 positive regulation of cell communication by chemical coupling
GO:0014704 intercalated disc
GO:0016264 gap junction assembly
GO:0030326 embryonic limb morphogenesis
GO:0035050 embryonic heart tube development
GO:0035922 foramen ovale closure
GO:0042995 cell projection
GO:0045776 negative regulation of blood pressure
GO:0045907 positive regulation of vasoconstriction
GO:0048844 artery morphogenesis
GO:0055077 gap junction hemi-channel activity
GO:0055117 regulation of cardiac muscle contraction
GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization
GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization
GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization
GO:0060412 ventricular septum morphogenesis
GO:0060413 atrial septum morphogenesis
GO:0061337 cardiac conduction
GO:0071253 connexin binding
GO:0086005 ventricular cardiac muscle cell action potential
GO:0086015 SA node cell action potential
GO:0086044 atrial cardiac muscle cell to AV node cell communication by electrical coupling
GO:0086053 AV node cell to bundle of His cell communication by electrical coupling
GO:0086054 bundle of His cell to Purkinje myocyte communication by electrical coupling
GO:0086064 cell communication by electrical coupling involved in cardiac conduction
GO:0086065 cell communication involved in cardiac conduction
GO:0086067 AV node cell to bundle of His cell communication
GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling
GO:0086076 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling
GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling
GO:0086078 gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling
GO:0086091 regulation of heart rate by cardiac conduction
GO:0097718 disordered domain specific binding
GO:0097746 blood vessel diameter maintenance
GO:0098904 regulation of AV node cell action potential
GO:0098905 regulation of bundle of His cell action potential
GO:0098906 regulation of Purkinje myocyte action potential
GO:0098910 regulation of atrial cardiac muscle cell action potential
GO:1900133 regulation of renin secretion into blood stream
GO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential
GO:1990029 vasomotion

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane

Domains

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DomainNameCategoryType
IPR000500 ConnexinFamilyFamily
IPR002264 Gap junction alpha-5 protein (Cx40)FamilyFamily
IPR013092 Connexin, N-terminalDomainDomain
IPR017990 Connexin, conserved siteSiteConserved site
IPR019570 Gap junction protein, cysteine-rich domainDomainDomain
IPR031862 Gap junction alpha-5 protein (Cx40), C-terminalDomainDomain
IPR034634 Connexin, C-terminalFamilyHomologous superfamily
IPR038359 Connexin, N-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink