Entity Details

Primary name ADA2C_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ01337
EntryNameADA2C_MOUSE
FullNameAlpha-2C adrenergic receptor
TaxID10090
Evidenceinferred from homology
Length458
SequenceStatuscomplete
DateCreated1993-04-01
DateModified2021-06-02

Ontological Relatives

GenesAdra2c

GO terms

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GOName
GO:0004930 G protein-coupled receptor activity
GO:0004938 alpha2-adrenergic receptor activity
GO:0005737 cytoplasm
GO:0005887 integral component of plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007565 female pregnancy
GO:0030168 platelet activation
GO:0030424 axon
GO:0031694 alpha-2A adrenergic receptor binding
GO:0032148 activation of protein kinase B activity
GO:0035624 receptor transactivation
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043025 neuronal cell body
GO:0043410 positive regulation of MAPK cascade
GO:0043679 axon terminus
GO:0045666 positive regulation of neuron differentiation
GO:0045907 positive regulation of vasoconstriction
GO:0046982 protein heterodimerization activity
GO:0051379 epinephrine binding
GO:0051930 regulation of sensory perception of pain
GO:0070473 negative regulation of uterine smooth muscle contraction
GO:0071875 adrenergic receptor signaling pathway
GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway
GO:0098978 glutamatergic synapse
GO:0099055 integral component of postsynaptic membrane
GO:0099061 integral component of postsynaptic density membrane

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000735 Alpha 2C adrenoceptorFamilyFamily
IPR002233 Adrenoceptor familyFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ADA2C_MOUSEEI2BA_HUMANIntAct9235896 details