Entity Details

Primary name CAC1C_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ01815
EntryNameCAC1C_MOUSE
FullNameVoltage-dependent L-type calcium channel subunit alpha-1C
TaxID10090
Evidenceevidence at protein level
Length2139
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesCacna1c

GO terms

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GOName
GO:0002095 caveolar macromolecular signaling complex
GO:0002520 immune system development
GO:0005245 voltage-gated calcium channel activity
GO:0005516 calmodulin binding
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005891 voltage-gated calcium channel complex
GO:0006816 calcium ion transport
GO:0006874 cellular calcium ion homeostasis
GO:0006939 smooth muscle contraction
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007268 chemical synaptic transmission
GO:0007507 heart development
GO:0007628 adult walking behavior
GO:0008217 regulation of blood pressure
GO:0008331 high voltage-gated calcium channel activity
GO:0008542 visual learning
GO:0009986 cell surface
GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0014069 postsynaptic density
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0017156 calcium-ion regulated exocytosis
GO:0019229 regulation of vasoconstriction
GO:0019899 enzyme binding
GO:0019904 protein domain specific binding
GO:0030018 Z disc
GO:0030073 insulin secretion
GO:0030252 growth hormone secretion
GO:0030315 T-tubule
GO:0030425 dendrite
GO:0031369 translation initiation factor binding
GO:0032991 protein-containing complex
GO:0035115 embryonic forelimb morphogenesis
GO:0042383 sarcolemma
GO:0042593 glucose homeostasis
GO:0042734 presynaptic membrane
GO:0043010 camera-type eye development
GO:0043025 neuronal cell body
GO:0043198 dendritic shaft
GO:0043204 perikaryon
GO:0044325 transmembrane transporter binding
GO:0045211 postsynaptic membrane
GO:0045762 positive regulation of adenylate cyclase activity
GO:0046620 regulation of organ growth
GO:0046872 metal ion binding
GO:0051393 alpha-actinin binding
GO:0051721 protein phosphatase 2A binding
GO:0060083 smooth muscle contraction involved in micturition
GO:0060402 calcium ion transport into cytosol
GO:0061337 cardiac conduction
GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel
GO:0070509 calcium ion import
GO:0070588 calcium ion transmembrane transport
GO:0086002 cardiac muscle cell action potential involved in contraction
GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential
GO:0086012 membrane depolarization during cardiac muscle cell action potential
GO:0086045 membrane depolarization during AV node cell action potential
GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential
GO:0086065 cell communication involved in cardiac conduction
GO:0086091 regulation of heart rate by cardiac conduction
GO:0098703 calcium ion import across plasma membrane
GO:0098839 postsynaptic density membrane
GO:0098911 regulation of ventricular cardiac muscle cell action potential
GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential
GO:0098978 glutamatergic synapse
GO:0099055 integral component of postsynaptic membrane
GO:0099056 integral component of presynaptic membrane
GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
GO:1905030 voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential
GO:1990454 L-type voltage-gated calcium channel complex

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cell projection
Perikaryon

Domains

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DomainNameCategoryType
IPR002077 Voltage-dependent calcium channel, alpha-1 subunitFamilyFamily
IPR005446 Voltage-dependent calcium channel, L-type, alpha-1 subunitFamilyFamily
IPR005451 Voltage-dependent calcium channel, L-type, alpha-1C subunitFamilyFamily
IPR005821 Ion transport domainDomainDomain
IPR014873 Voltage-dependent calcium channel, alpha-1 subunit, IQ domainDomainDomain
IPR027359 Voltage-dependent channel domain superfamilyFamilyHomologous superfamily
IPR031649 Voltage-dependent L-type calcium channel, IQ-associated domainDomainDomain
IPR031688 Voltage-gated calcium channel subunit alpha, C-terminalDomainDomain

Diseases

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