Entity Details

Primary name KPCT_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ02111
EntryNameKPCT_MOUSE
FullNameProtein kinase C theta type
TaxID10090
Evidenceevidence at protein level
Length707
SequenceStatuscomplete
DateCreated1993-07-01
DateModified2021-06-02

Ontological Relatives

GenesPrkcq

GO terms

Show/Hide Table
GOName
GO:0001772 immunological synapse
GO:0002376 immune system process
GO:0004674 protein serine/threonine kinase activity
GO:0004697 protein kinase C activity
GO:0004698 calcium-dependent protein kinase C activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0006355 regulation of transcription, DNA-templated
GO:0006468 protein phosphorylation
GO:0006509 membrane protein ectodomain proteolysis
GO:0006954 inflammatory response
GO:0010389 regulation of G2/M transition of mitotic cell cycle
GO:0016020 membrane
GO:0016235 aggresome
GO:0018105 peptidyl-serine phosphorylation
GO:0031594 neuromuscular junction
GO:0032212 positive regulation of telomere maintenance via telomerase
GO:0032740 positive regulation of interleukin-17 production
GO:0032743 positive regulation of interleukin-2 production
GO:0032753 positive regulation of interleukin-4 production
GO:0034451 centriolar satellite
GO:0035556 intracellular signal transduction
GO:0042102 positive regulation of T cell proliferation
GO:0042307 positive regulation of protein import into nucleus
GO:0042383 sarcolemma
GO:0046627 negative regulation of insulin receptor signaling pathway
GO:0046872 metal ion binding
GO:0050714 positive regulation of protein secretion
GO:0050870 positive regulation of T cell activation
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051491 positive regulation of filopodium assembly
GO:0051496 positive regulation of stress fiber assembly
GO:0051973 positive regulation of telomerase activity
GO:0060326 cell chemotaxis
GO:0070233 negative regulation of T cell apoptotic process
GO:0090330 regulation of platelet aggregation
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1904355 positive regulation of telomere capping
GO:2000318 positive regulation of T-helper 17 type immune response
GO:2000570 positive regulation of T-helper 2 cell activation

Subcellular Location

Show/Hide Table
Subcellular Location
Cell membrane
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR000961 AGC-kinase, C-terminalDomainDomain
IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR014376 Protein kinase C, delta/epsilon/eta/theta typesFamilyFamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR017892 Protein kinase, C-terminalDomainDomain
IPR020454 Diacylglycerol/phorbol-ester bindingDomainDomain
IPR027264 Protein kinase C, thetaFamilyFamily
IPR034668 Novel protein kinase C theta, catalytic domainDomainDomain
IPR035892 C2 domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table