Entity Details

Primary name 5HT2B_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ02152
EntryName5HT2B_MOUSE
FullName5-hydroxytryptamine receptor 2B
TaxID10090
Evidenceevidence at protein level
Length479
SequenceStatuscomplete
DateCreated1993-07-01
DateModified2021-06-02

Ontological Relatives

GenesHtr2b

GO terms

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GOName
GO:0001587 Gq/11-coupled serotonin receptor activity
GO:0001755 neural crest cell migration
GO:0001819 positive regulation of cytokine production
GO:0001938 positive regulation of endothelial cell proliferation
GO:0001965 G-protein alpha-subunit binding
GO:0002031 G protein-coupled receptor internalization
GO:0003007 heart morphogenesis
GO:0003300 cardiac muscle hypertrophy
GO:0004993 G protein-coupled serotonin receptor activity
GO:0005096 GTPase activator activity
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006874 cellular calcium ion homeostasis
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
GO:0007202 activation of phospholipase C activity
GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway
GO:0007208 phospholipase C-activating serotonin receptor signaling pathway
GO:0007268 chemical synaptic transmission
GO:0007507 heart development
GO:0007610 behavior
GO:0008284 positive regulation of cell population proliferation
GO:0010507 negative regulation of autophagy
GO:0010513 positive regulation of phosphatidylinositol biosynthetic process
GO:0014033 neural crest cell differentiation
GO:0014065 phosphatidylinositol 3-kinase signaling
GO:0014827 intestine smooth muscle contraction
GO:0016020 membrane
GO:0016310 phosphorylation
GO:0019722 calcium-mediated signaling
GO:0019934 cGMP-mediated signaling
GO:0030425 dendrite
GO:0030594 neurotransmitter receptor activity
GO:0034220 ion transmembrane transport
GO:0042310 vasoconstriction
GO:0042493 response to drug
GO:0043025 neuronal cell body
GO:0043066 negative regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043406 positive regulation of MAP kinase activity
GO:0045202 synapse
GO:0048598 embryonic morphogenesis
GO:0050795 regulation of behavior
GO:0051000 positive regulation of nitric-oxide synthase activity
GO:0051209 release of sequestered calcium ion into cytosol
GO:0051378 serotonin binding
GO:0051781 positive regulation of cell division
GO:0060548 negative regulation of cell death
GO:0070371 ERK1 and ERK2 cascade
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070528 protein kinase C signaling
GO:0071418 cellular response to amine stimulus
GO:0071502 cellular response to temperature stimulus
GO:0098664 G protein-coupled serotonin receptor signaling pathway
GO:0098666 G protein-coupled serotonin receptor complex
GO:1904015 cellular response to serotonin

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000482 5-Hydroxytryptamine 2B receptorFamilyFamily
IPR002231 5-hydroxytryptamine receptor familyFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Interactions

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