Entity Details

Primary name PAX5_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ02650
EntryNamePAX5_MOUSE
FullNamePaired box protein Pax-5
TaxID10090
Evidenceevidence at protein level
Length391
SequenceStatuscomplete
DateCreated1993-07-01
DateModified2021-06-02

Ontological Relatives

GenesPax5

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001650 fibrillar center
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005829 cytosol
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007283 spermatogenesis
GO:0007568 aging
GO:0009887 animal organ morphogenesis
GO:0021670 lateral ventricle development
GO:0021987 cerebral cortex development
GO:0030534 adult behavior
GO:0035914 skeletal muscle cell differentiation
GO:0043231 intracellular membrane-bounded organelle
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048701 embryonic cranial skeleton morphogenesis
GO:0048856 anatomical structure development
GO:0051573 negative regulation of histone H3-K9 methylation
GO:0071542 dopaminergic neuron differentiation

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001523 Paired domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR022130 Paired-box protein 2 C-terminalDomainDomain
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR043182 Paired DNA-binding domainDomainDomain
IPR043565 PAX familyFamilyFamily

Diseases

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