Entity Details

Primary name FGFR4_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ03142
EntryNameFGFR4_MOUSE
FullNameFibroblast growth factor receptor 4
TaxID10090
Evidenceevidence at protein level
Length799
SequenceStatuscomplete
DateCreated1994-10-01
DateModified2021-06-02

Ontological Relatives

GenesFgfr4

GO terms

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GOName
GO:0001759 organ induction
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005007 fibroblast growth factor-activated receptor activity
GO:0005524 ATP binding
GO:0005768 endosome
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007275 multicellular organism development
GO:0008201 heparin binding
GO:0008284 positive regulation of cell population proliferation
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0010715 regulation of extracellular matrix disassembly
GO:0010966 regulation of phosphate transport
GO:0016477 cell migration
GO:0017134 fibroblast growth factor binding
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0019216 regulation of lipid metabolic process
GO:0030133 transport vesicle
GO:0030324 lung development
GO:0033674 positive regulation of kinase activity
GO:0042593 glucose homeostasis
GO:0042632 cholesterol homeostasis
GO:0043085 positive regulation of catalytic activity
GO:0043235 receptor complex
GO:0045862 positive regulation of proteolysis
GO:0046777 protein autophosphorylation
GO:0051174 regulation of phosphorus metabolic process
GO:0055062 phosphate ion homeostasis
GO:0061144 alveolar secondary septum development
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070640 vitamin D3 metabolic process
GO:0070857 regulation of bile acid biosynthetic process
GO:0090272 negative regulation of fibroblast growth factor production
GO:2000573 positive regulation of DNA biosynthetic process
GO:2000830 positive regulation of parathyroid hormone secretion

Subcellular Location

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Subcellular Location
Cell membrane
Endoplasmic reticulum
Endosome

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domainDomainDomain
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR008266 Tyrosine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR013098 Immunoglobulin I-setDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR016248 Fibroblast growth factor receptor familyFamilyFamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR020635 Tyrosine-protein kinase, catalytic domainDomainDomain
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions