Entity Details

Primary name RUNX1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ03347
EntryNameRUNX1_MOUSE
FullNameRunt-related transcription factor 1
TaxID10090
Evidenceevidence at protein level
Length451
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GO terms

Show/Hide Table
GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000976 transcription cis-regulatory region binding
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001501 skeletal system development
GO:0001503 ossification
GO:0001701 in utero embryonic development
GO:0001889 liver development
GO:0002062 chondrocyte differentiation
GO:0002318 myeloid progenitor cell differentiation
GO:0002667 regulation of T cell anergy
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005509 calcium ion binding
GO:0005524 ATP binding
GO:0005604 basement membrane
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007417 central nervous system development
GO:0008134 transcription factor binding
GO:0008285 negative regulation of cell population proliferation
GO:0009966 regulation of signal transduction
GO:0016513 core-binding factor complex
GO:0030097 hemopoiesis
GO:0030099 myeloid cell differentiation
GO:0030182 neuron differentiation
GO:0030853 negative regulation of granulocyte differentiation
GO:0030854 positive regulation of granulocyte differentiation
GO:0031069 hair follicle morphogenesis
GO:0032526 response to retinoic acid
GO:0032729 positive regulation of interferon-gamma production
GO:0032743 positive regulation of interleukin-2 production
GO:0032991 protein-containing complex
GO:0035162 embryonic hemopoiesis
GO:0042803 protein homodimerization activity
GO:0043231 intracellular membrane-bounded organelle
GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation
GO:0043378 positive regulation of CD8-positive, alpha-beta T cell differentiation
GO:0045595 regulation of cell differentiation
GO:0045766 positive regulation of angiogenesis
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046982 protein heterodimerization activity
GO:0048266 behavioral response to pain
GO:0048663 neuron fate commitment
GO:0048666 neuron development
GO:0060216 definitive hemopoiesis
GO:0071336 regulation of hair follicle cell proliferation
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:0140297 DNA-binding transcription factor binding
GO:1903431 positive regulation of cell maturation
GO:1990837 sequence-specific double-stranded DNA binding
GO:1990841 promoter-specific chromatin binding
GO:2000872 positive regulation of progesterone secretion

Subcellular Location

Show/Hide Table
Subcellular Location
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR000040 Acute myeloid leukemia 1 protein (AML1)/RuntFamilyFamily
IPR008967 p53-like transcription factor, DNA-bindingFamilyHomologous superfamily
IPR012346 p53/RUNT-type transcription factor, DNA-binding domain superfamilyFamilyHomologous superfamily
IPR013524 Runt domainDomainDomain
IPR013711 Runx, C-terminal domainDomainDomain
IPR016554 Runt-related transcription factor RUNXFamilyFamily
IPR027384 Runx, central domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

3 interactions