Entity Details

Primary name MSX2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ03358
EntryNameMSX2_MOUSE
FullNameHomeobox protein MSX-2
TaxID10090
Evidenceevidence at protein level
Length267
SequenceStatuscomplete
DateCreated1993-10-01
DateModified2021-06-02

Ontological Relatives

GenesMsx2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000976 transcription cis-regulatory region binding
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001503 ossification
GO:0001649 osteoblast differentiation
GO:0002063 chondrocyte development
GO:0002076 osteoblast development
GO:0003148 outflow tract septum morphogenesis
GO:0003151 outflow tract morphogenesis
GO:0003198 epithelial to mesenchymal transition involved in endocardial cushion formation
GO:0003416 endochondral bone growth
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006366 transcription by RNA polymerase II
GO:0008134 transcription factor binding
GO:0008285 negative regulation of cell population proliferation
GO:0009952 anterior/posterior pattern specification
GO:0010942 positive regulation of cell death
GO:0016607 nuclear speck
GO:0023019 signal transduction involved in regulation of gene expression
GO:0030326 embryonic limb morphogenesis
GO:0030509 BMP signaling pathway
GO:0030513 positive regulation of BMP signaling pathway
GO:0032792 negative regulation of CREB transcription factor activity
GO:0035115 embryonic forelimb morphogenesis
GO:0035116 embryonic hindlimb morphogenesis
GO:0035313 wound healing, spreading of epidermal cells
GO:0035880 embryonic nail plate morphogenesis
GO:0042060 wound healing
GO:0042476 odontogenesis
GO:0042733 embryonic digit morphogenesis
GO:0042981 regulation of apoptotic process
GO:0043065 positive regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043565 sequence-specific DNA binding
GO:0045599 negative regulation of fat cell differentiation
GO:0045617 negative regulation of keratinocyte differentiation
GO:0045669 positive regulation of osteoblast differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0048598 embryonic morphogenesis
GO:0048863 stem cell differentiation
GO:0051216 cartilage development
GO:0051795 positive regulation of timing of catagen
GO:0060346 bone trabecula formation
GO:0060349 bone morphogenesis
GO:0060364 frontal suture morphogenesis
GO:0060444 branching involved in mammary gland duct morphogenesis
GO:0061180 mammary gland epithelium development
GO:0061312 BMP signaling pathway involved in heart development
GO:0070166 enamel mineralization
GO:0071363 cellular response to growth factor stimulus
GO:0071392 cellular response to estradiol stimulus
GO:0090427 activation of meiosis
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000678 negative regulation of transcription regulatory region DNA binding
GO:2001055 positive regulation of mesenchymal cell apoptotic process

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site
IPR020479 Homeobox domain, metazoaDomainDomain

Diseases

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