Entity Details

Primary name PCSK5_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ04592
EntryNamePCSK5_MOUSE
FullNameProprotein convertase subtilisin/kexin type 5
TaxID10090
Evidenceevidence at protein level
Length1877
SequenceStatuscomplete
DateCreated1995-02-01
DateModified2021-06-02

Ontological Relatives

GenesPcsk5

GO terms

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GOName
GO:0001822 kidney development
GO:0003279 cardiac septum development
GO:0004175 endopeptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0005615 extracellular space
GO:0005788 endoplasmic reticulum lumen
GO:0005794 Golgi apparatus
GO:0005797 Golgi medial cisterna
GO:0005802 trans-Golgi network
GO:0005886 plasma membrane
GO:0006465 signal peptide processing
GO:0007368 determination of left/right symmetry
GO:0007507 heart development
GO:0007566 embryo implantation
GO:0008233 peptidase activity
GO:0009952 anterior/posterior pattern specification
GO:0016020 membrane
GO:0016485 protein processing
GO:0016486 peptide hormone processing
GO:0019058 viral life cycle
GO:0030141 secretory granule
GO:0030173 integral component of Golgi membrane
GO:0030323 respiratory tube development
GO:0033625 positive regulation of integrin activation
GO:0035108 limb morphogenesis
GO:0042277 peptide binding
GO:0043043 peptide biosynthetic process
GO:0043204 perikaryon
GO:0048566 embryonic digestive tract development
GO:0048706 embryonic skeletal system development
GO:0060976 coronary vasculature development
GO:0140447 cytokine precursor processing
GO:1904754 positive regulation of vascular associated smooth muscle cell migration
GO:1905609 positive regulation of smooth muscle cell-matrix adhesion
GO:1990635 proximal dendrite
GO:2001046 positive regulation of integrin-mediated signaling pathway

Subcellular Location

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Subcellular Location
Endomembrane system
Secreted

Domains

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DomainNameCategoryType
IPR000209 Peptidase S8/S53 domainDomainDomain
IPR000742 EGF-like domainDomainDomain
IPR002884 P domainDomainDomain
IPR006212 Furin-like repeatRepeatRepeat
IPR008979 Galactose-binding-like domain superfamilyFamilyHomologous superfamily
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR015500 Peptidase S8, subtilisin-relatedFamilyFamily
IPR022398 Peptidase S8, subtilisin, His-active siteSiteActive site
IPR023827 Peptidase S8, subtilisin, Asp-active siteSiteActive site
IPR023828 Peptidase S8, subtilisin, Ser-active siteSiteActive site
IPR032778 Growth factor receptor domain 4DomainDomain
IPR032815 Peptidase S8, pro-domainDomainDomain
IPR034182 Kexin/furin catalytic domainDomainDomain
IPR036852 Peptidase S8/S53 domain superfamilyFamilyHomologous superfamily
IPR038466 Peptidase S8, pro-domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

4 interactions