Entity Details

Primary name YES_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ04736
EntryNameYES_MOUSE
FullNameTyrosine-protein kinase Yes
TaxID10090
Evidenceevidence at protein level
Length541
SequenceStatuscomplete
DateCreated1993-10-01
DateModified2021-06-02

Ontological Relatives

GenesYes1

GO terms

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GOName
GO:0001784 phosphotyrosine residue binding
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005102 signaling receptor binding
GO:0005154 epidermal growth factor receptor binding
GO:0005524 ATP binding
GO:0005794 Golgi apparatus
GO:0005815 microtubule organizing center
GO:0005829 cytosol
GO:0005884 actin filament
GO:0005886 plasma membrane
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0010827 regulation of glucose transmembrane transport
GO:0019899 enzyme binding
GO:0030154 cell differentiation
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
GO:0036120 cellular response to platelet-derived growth factor stimulus
GO:0044325 transmembrane transporter binding
GO:0045087 innate immune response
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046777 protein autophosphorylation
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0071300 cellular response to retinoic acid
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:0098978 glutamatergic synapse
GO:0099091 postsynaptic specialization, intracellular component

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR000980 SH2 domainDomainDomain
IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domainDomainDomain
IPR001452 SH3 domainDomainDomain
IPR008266 Tyrosine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR020635 Tyrosine-protein kinase, catalytic domainDomainDomain
IPR035751 Tyrosine-protein kinase Yes, SH3 domainDomainDomain
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR036860 SH2 domain superfamilyFamilyHomologous superfamily

Diseases

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