Entity Details

Primary name PRRX2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ06348
EntryNamePRRX2_MOUSE
FullNamePaired mesoderm homeobox protein 2
TaxID10090
Evidenceevidence at transcript level
Length247
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesPrrx2

GO terms

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GOName
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0002053 positive regulation of mesenchymal cell proliferation
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0030326 embryonic limb morphogenesis
GO:0042472 inner ear morphogenesis
GO:0042474 middle ear morphogenesis
GO:0045880 positive regulation of smoothened signaling pathway
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048701 embryonic cranial skeleton morphogenesis
GO:0048704 embryonic skeletal system morphogenesis
GO:0048844 artery morphogenesis
GO:0051216 cartilage development
GO:0071837 HMG box domain binding
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR003654 OAR domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site
IPR043378 Paired mesoderm homeobox protein 1/2FamilyFamily

Diseases

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Interactions

3 interactions