Entity Details

Primary name IBP5_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ07079
EntryNameIBP5_MOUSE
FullNameInsulin-like growth factor-binding protein 5
TaxID10090
Evidenceevidence at protein level
Length271
SequenceStatuscomplete
DateCreated1994-10-01
DateModified2021-06-02

Ontological Relatives

GenesIgfbp5

GO terms

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GOName
GO:0001558 regulation of cell growth
GO:0001649 osteoblast differentiation
GO:0001968 fibronectin binding
GO:0005520 insulin-like growth factor binding
GO:0005615 extracellular space
GO:0007565 female pregnancy
GO:0007568 aging
GO:0014912 negative regulation of smooth muscle cell migration
GO:0016942 insulin-like growth factor binding protein complex
GO:0017148 negative regulation of translation
GO:0030336 negative regulation of cell migration
GO:0031069 hair follicle morphogenesis
GO:0031994 insulin-like growth factor I binding
GO:0031995 insulin-like growth factor II binding
GO:0035556 intracellular signal transduction
GO:0040008 regulation of growth
GO:0042567 insulin-like growth factor ternary complex
GO:0042593 glucose homeostasis
GO:0043567 regulation of insulin-like growth factor receptor signaling pathway
GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway
GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway
GO:0044342 type B pancreatic cell proliferation
GO:0045668 negative regulation of osteoblast differentiation
GO:0045926 negative regulation of growth
GO:0048286 lung alveolus development
GO:0048662 negative regulation of smooth muscle cell proliferation
GO:0051146 striated muscle cell differentiation
GO:0051897 positive regulation of protein kinase B signaling
GO:0060056 mammary gland involution
GO:0060416 response to growth hormone
GO:0071320 cellular response to cAMP
GO:0071407 cellular response to organic cyclic compound
GO:1901862 negative regulation of muscle tissue development
GO:1904205 negative regulation of skeletal muscle hypertrophy
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation
GO:1904754 positive regulation of vascular associated smooth muscle cell migration

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000716 Thyroglobulin type-1DomainDomain
IPR000867 Insulin-like growth factor-binding protein, IGFBPDomainDomain
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR012213 Insulin-like growth factor binding protein 5FamilyFamily
IPR017891 Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved siteSiteConserved site
IPR022321 Insulin-like growth factor-binding protein family 1-6, chordataFamilyFamily
IPR036857 Thyroglobulin type-1 superfamilyFamilyHomologous superfamily

Diseases

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Interactions

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