Entity Details

Primary name GDF3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ07104
EntryNameGDF3_MOUSE
FullNameGrowth/differentiation factor 3
TaxID10090
Evidenceevidence at protein level
Length366
SequenceStatuscomplete
DateCreated1994-10-01
DateModified2021-06-02

Ontological Relatives

GenesGdf3

GO terms

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GOName
GO:0001501 skeletal system development
GO:0001654 eye development
GO:0001701 in utero embryonic development
GO:0002021 response to dietary excess
GO:0005125 cytokine activity
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0007165 signal transduction
GO:0007492 endoderm development
GO:0007498 mesoderm development
GO:0008083 growth factor activity
GO:0010453 regulation of cell fate commitment
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0019901 protein kinase binding
GO:0030509 BMP signaling pathway
GO:0030514 negative regulation of BMP signaling pathway
GO:0030903 notochord development
GO:0032525 somite rostral/caudal axis specification
GO:0045600 positive regulation of fat cell differentiation
GO:0045605 negative regulation of epidermal cell differentiation
GO:0045662 negative regulation of myoblast differentiation
GO:0048859 formation of anatomical boundary
GO:0060395 SMAD protein signal transduction
GO:0090009 primitive streak formation

Subcellular Location

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Subcellular Location
Cytoplasm
Secreted

Domains

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DomainNameCategoryType
IPR001839 Transforming growth factor-beta, C-terminalDomainDomain
IPR015615 Transforming growth factor-beta-relatedFamilyFamily
IPR017948 Transforming growth factor beta, conserved siteSiteConserved site
IPR029034 Cystine-knot cytokineFamilyHomologous superfamily

Diseases

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Interactions

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InteractorPartnerSourcesPublicationsLink