Entity Details

Primary name BAX_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ07813
EntryNameBAX_MOUSE
FullNameApoptosis regulator BAX
TaxID10090
Evidenceevidence at protein level
Length192
SequenceStatuscomplete
DateCreated1995-02-01
DateModified2021-06-02

Ontological Relatives

GenesBax

GO terms

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GOName
GO:0001541 ovarian follicle development
GO:0001764 neuron migration
GO:0001776 leukocyte homeostasis
GO:0001777 T cell homeostatic proliferation
GO:0001782 B cell homeostasis
GO:0001783 B cell apoptotic process
GO:0001822 kidney development
GO:0001836 release of cytochrome c from mitochondria
GO:0001844 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:0001974 blood vessel remodeling
GO:0002262 myeloid cell homeostasis
GO:0002352 B cell negative selection
GO:0002358 B cell homeostatic proliferation
GO:0002904 positive regulation of B cell apoptotic process
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005757 mitochondrial permeability transition pore complex
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0006687 glycosphingolipid metabolic process
GO:0006808 regulation of nitrogen utilization
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006974 cellular response to DNA damage stimulus
GO:0007007 inner mitochondrial membrane organization
GO:0007008 outer mitochondrial membrane organization
GO:0007281 germ cell development
GO:0007283 spermatogenesis
GO:0007399 nervous system development
GO:0007548 sex differentiation
GO:0008053 mitochondrial fusion
GO:0008283 cell population proliferation
GO:0008285 negative regulation of cell population proliferation
GO:0008289 lipid binding
GO:0008584 male gonad development
GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
GO:0008637 apoptotic mitochondrial changes
GO:0009566 fertilization
GO:0009611 response to wounding
GO:0009636 response to toxic substance
GO:0009651 response to salt stress
GO:0009791 post-embryonic development
GO:0010212 response to ionizing radiation
GO:0010248 establishment or maintenance of transmembrane electrochemical gradient
GO:0010332 response to gamma radiation
GO:0010524 positive regulation of calcium ion transport into cytosol
GO:0010917 negative regulation of mitochondrial membrane potential
GO:0015267 channel activity
GO:0016021 integral component of membrane
GO:0016032 viral process
GO:0021854 hypothalamus development
GO:0021987 cerebral cortex development
GO:0030544 Hsp70 protein binding
GO:0031072 heat shock protein binding
GO:0031334 positive regulation of protein-containing complex assembly
GO:0031966 mitochondrial membrane
GO:0032091 negative regulation of protein binding
GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration
GO:0032976 release of matrix enzymes from mitochondria
GO:0033137 negative regulation of peptidyl-serine phosphorylation
GO:0033599 regulation of mammary gland epithelial cell proliferation
GO:0034644 cellular response to UV
GO:0035108 limb morphogenesis
GO:0035234 ectopic germ cell programmed cell death
GO:0042475 odontogenesis of dentin-containing tooth
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0042981 regulation of apoptotic process
GO:0043065 positive regulation of apoptotic process
GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043523 regulation of neuron apoptotic process
GO:0043524 negative regulation of neuron apoptotic process
GO:0043525 positive regulation of neuron apoptotic process
GO:0043653 mitochondrial fragmentation involved in apoptotic process
GO:0044877 protein-containing complex binding
GO:0045136 development of secondary sexual characteristics
GO:0045333 cellular respiration
GO:0046666 retinal cell programmed cell death
GO:0046930 pore complex
GO:0046982 protein heterodimerization activity
GO:0048087 positive regulation of developmental pigmentation
GO:0048147 negative regulation of fibroblast proliferation
GO:0048471 perinuclear region of cytoplasm
GO:0048515 spermatid differentiation
GO:0048597 post-embryonic camera-type eye morphogenesis
GO:0048678 response to axon injury
GO:0048872 homeostasis of number of cells
GO:0048873 homeostasis of number of cells within a tissue
GO:0051087 chaperone binding
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
GO:0051400 BH domain binding
GO:0051402 neuron apoptotic process
GO:0051434 BH3 domain binding
GO:0051726 regulation of cell cycle
GO:0060011 Sertoli cell proliferation
GO:0060041 retina development in camera-type eye
GO:0060058 positive regulation of apoptotic process involved in mammary gland involution
GO:0060068 vagina development
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0070242 thymocyte apoptotic process
GO:0070584 mitochondrion morphogenesis
GO:0071310 cellular response to organic substance
GO:0071944 cell periphery
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator
GO:0090200 positive regulation of release of cytochrome c from mitochondria
GO:0097136 Bcl-2 family protein complex
GO:0097144 BAX complex
GO:0097145 BAK complex
GO:0097190 apoptotic signaling pathway
GO:0097191 extrinsic apoptotic signaling pathway
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
GO:0097193 intrinsic apoptotic signaling pathway
GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
GO:0098586 cellular response to virus
GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response
GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process
GO:1902110 positive regulation of mitochondrial membrane permeability involved in apoptotic process
GO:1902262 apoptotic process involved in blood vessel morphogenesis
GO:1902263 apoptotic process involved in embryonic digit morphogenesis
GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death
GO:1902512 positive regulation of apoptotic DNA fragmentation
GO:1990117 B cell receptor apoptotic signaling pathway
GO:2001234 negative regulation of apoptotic signaling pathway
GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasm
Mitochondrion outer membrane

Domains

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DomainNameCategoryType
IPR002475 Bcl2-likeFamilyFamily
IPR020717 Apoptosis regulator, Bcl-2, BH1 motif, conserved siteSiteConserved site
IPR020726 Apoptosis regulator, Bcl-2, BH2 motif, conserved siteSiteConserved site
IPR020728 Apoptosis regulator, Bcl-2, BH3 motif, conserved siteSiteConserved site
IPR026298 Bcl-2 familyFamilyFamily
IPR026304 Apoptosis regulator BAXFamilyFamily
IPR036834 Bcl-2-like superfamilyFamilyHomologous superfamily

Diseases

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