Entity Details

Primary name HGF_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ08048
EntryNameHGF_MOUSE
FullNameHepatocyte growth factor
TaxID10090
Evidenceevidence at protein level
Length728
SequenceStatuscomplete
DateCreated1995-11-01
DateModified2021-06-02

Ontological Relatives

GenesHgf

GO terms

Show/Hide Table
GOName
GO:0000187 obsolete activation of MAPK activity
GO:0000902 cell morphogenesis
GO:0001889 liver development
GO:0001934 positive regulation of protein phosphorylation
GO:0004252 serine-type endopeptidase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0008083 growth factor activity
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0030212 hyaluronan metabolic process
GO:0030335 positive regulation of cell migration
GO:0031100 animal organ regeneration
GO:0031643 positive regulation of myelination
GO:0032715 negative regulation of interleukin-6 production
GO:0032733 positive regulation of interleukin-10 production
GO:0033137 negative regulation of peptidyl-serine phosphorylation
GO:0035729 cellular response to hepatocyte growth factor stimulus
GO:0042056 chemoattractant activity
GO:0042802 identical protein binding
GO:0043066 negative regulation of apoptotic process
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0044877 protein-containing complex binding
GO:0045766 positive regulation of angiogenesis
GO:0048012 hepatocyte growth factor receptor signaling pathway
GO:0050673 epithelial cell proliferation
GO:0050728 negative regulation of inflammatory response
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0051450 myoblast proliferation
GO:0060326 cell chemotaxis
GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
GO:0070572 positive regulation of neuron projection regeneration
GO:0090201 negative regulation of release of cytochrome c from mitochondria
GO:1900744 regulation of p38MAPK cascade
GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1902947 regulation of tau-protein kinase activity
GO:2000573 positive regulation of DNA biosynthetic process

Subcellular Location

Show/Hide Table

Domains

Show/Hide Table
DomainNameCategoryType
IPR000001 KringleDomainDomain
IPR001254 Serine proteases, trypsin domainDomainDomain
IPR001314 Peptidase S1A, chymotrypsin familyFamilyFamily
IPR003609 PAN/Apple domainDomainDomain
IPR009003 Peptidase S1, PA clanFamilyHomologous superfamily
IPR013806 Kringle-like foldFamilyHomologous superfamily
IPR018056 Kringle, conserved siteSiteConserved site
IPR024174 Hepatocyte growth factor/Macrophage stimulatory proteinFamilyFamily
IPR027284 Hepatocyte growth factorFamilyFamily
IPR038178 Kringle superfamilyFamilyHomologous superfamily
IPR043504 Peptidase S1, PA clan, chymotrypsin-like foldFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
HGF_MOUSEMET_HUMANDIP17804794 details
HGF_MOUSEHGF_MOUSEDIP17804794 details