Entity Details

Primary name TLE3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ08122
EntryNameTLE3_MOUSE
FullNameTransducin-like enhancer protein 3
TaxID10090
Evidenceevidence at protein level
Length772
SequenceStatuscomplete
DateCreated1995-02-01
DateModified2021-06-02

Ontological Relatives

GenesTle3

GO terms

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GOName
GO:0003714 transcription corepressor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0006355 regulation of transcription, DNA-templated
GO:0007275 multicellular organism development
GO:0007283 spermatogenesis
GO:0016055 Wnt signaling pathway
GO:0030154 cell differentiation
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0120163 negative regulation of cold-induced thermogenesis
GO:1990907 beta-catenin-TCF complex

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001680 WD40 repeatRepeatRepeat
IPR005617 Groucho/TLE, N-terminal Q-rich domainDomainDomain
IPR009146 Groucho/transducin-like enhancerFamilyFamily
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR019775 WD40 repeat, conserved siteSiteConserved site
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
TLE3_MOUSENKX22_MOUSEBioGRID17202186 details