Entity Details

Primary name KCMA1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ08460
EntryNameKCMA1_MOUSE
FullNameCalcium-activated potassium channel subunit alpha-1
TaxID10090
Evidenceevidence at protein level
Length1209
SequenceStatuscomplete
DateCreated2004-04-13
DateModified2021-06-02

Ontological Relatives

GenesKcnma1

GO terms

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GOName
GO:0001666 response to hypoxia
GO:0003779 actin binding
GO:0005249 voltage-gated potassium channel activity
GO:0005267 potassium channel activity
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0005901 caveola
GO:0006813 potassium ion transport
GO:0006970 response to osmotic stress
GO:0007268 chemical synaptic transmission
GO:0007605 sensory perception of sound
GO:0007623 circadian rhythm
GO:0007628 adult walking behavior
GO:0008076 voltage-gated potassium channel complex
GO:0009268 response to pH
GO:0009897 external side of plasma membrane
GO:0015269 calcium-activated potassium channel activity
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0019228 neuronal action potential
GO:0030007 cellular potassium ion homeostasis
GO:0030425 dendrite
GO:0031960 response to corticosteroid
GO:0032344 regulation of aldosterone metabolic process
GO:0032991 protein-containing complex
GO:0034465 response to carbon monoxide
GO:0034765 regulation of ion transmembrane transport
GO:0042311 vasodilation
GO:0042391 regulation of membrane potential
GO:0042491 inner ear auditory receptor cell differentiation
GO:0042802 identical protein binding
GO:0043025 neuronal cell body
GO:0043065 positive regulation of apoptotic process
GO:0043195 terminal bouton
GO:0043525 positive regulation of neuron apoptotic process
GO:0043627 response to estrogen
GO:0044877 protein-containing complex binding
GO:0045211 postsynaptic membrane
GO:0045475 locomotor rhythm
GO:0045794 negative regulation of cell volume
GO:0046541 saliva secretion
GO:0046872 metal ion binding
GO:0048469 cell maturation
GO:0048471 perinuclear region of cytoplasm
GO:0048787 presynaptic active zone membrane
GO:0050885 neuromuscular process controlling balance
GO:0051592 response to calcium ion
GO:0060072 large conductance calcium-activated potassium channel activity
GO:0060073 micturition
GO:0060082 eye blink reflex
GO:0060083 smooth muscle contraction involved in micturition
GO:0060087 relaxation of vascular associated smooth muscle
GO:0097746 blood vessel diameter maintenance
GO:0098978 glutamatergic synapse
GO:0099059 integral component of presynaptic active zone membrane
GO:0099507 ligand-gated ion channel activity involved in regulation of presynaptic membrane potential
GO:1904348 negative regulation of small intestine smooth muscle contraction

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR003929 Calcium-activated potassium channel BK, alpha subunitDomainDomain
IPR005821 Ion transport domainDomainDomain
IPR024939 Calcium-activated potassium channel Slo-1FamilyFamily
IPR027359 Voltage-dependent channel domain superfamilyFamilyHomologous superfamily
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB08837 TetraethylammoniumDrugbanksmall molecule

Interactions

32 interactions

InteractorPartnerSourcesPublicationsLink
KCMA1_MOUSEGRAP2_HUMANMINT17065230 details
KCMA1_MOUSESH3G1_HUMANMINT17065230 details
KCMA1_MOUSECRKL_HUMANMINT17065230 details
KCMA1_MOUSEP53_MOUSEBioGRID25581503 details
KCMA1_MOUSEFADD_MOUSEBioGRID25581503 details
KCMA1_MOUSENPHN_MOUSEBioGRID18480178 details
KCMA1_MOUSEMAP1A_MOUSEMINT15251455 details
KCMA1_MOUSECALM1_MOUSEBioGRID, IntAct19423573 details
KCMA1_MOUSECALM2_MOUSEBioGRID, IntAct19423573 details
KCMA1_MOUSECALM3_MOUSEBioGRID, IntAct19423573 details
KCMA1_MOUSEMYP0_MOUSEBioGRID, IntAct19423573 details
KCMA1_MOUSELIN7C_MOUSEBioGRID, IntAct19423573 details
KCMA1_MOUSEAPOA1_MOUSEBioGRID, IntAct19423573 details
KCMA1_MOUSE1433G_MOUSEBioGRID, IntAct19423573 details
KCMA1_MOUSEACTG_MOUSEBioGRID, IntAct19423573 details
KCMA1_MOUSEANXA5_MOUSEBioGRID, IntAct19423573 details
KCMA1_MOUSEG3P_MOUSEBioGRID, IntAct19423573 details
KCMA1_MOUSEHPCA_MOUSEIntAct19423573 details
KCMA1_MOUSESRC8_HUMANMINT17065230 details
KCMA1_MOUSEACTS_HUMANMINT17065230 details
KCMA1_MOUSESRC8_MOUSEMINT17065230 details
KCMA1_MOUSEKCMB1_MOUSEDIP16549765 18669652 details
KCMA1_MOUSETBA1A_MOUSEBioGRID19423573 details
KCMA1_MOUSEAMRP_MOUSEBioGRID19423573 details
KCMA1_MOUSEPSD11_MOUSEBioGRID19423573 details
KCMA1_MOUSEANXA7_MOUSEBioGRID19423573 details
KCMA1_MOUSEKCRM_MOUSEBioGRID19423573 details
KCMA1_MOUSEMET7B_MOUSEBioGRID19423573 details
KCMA1_MOUSECO1A2_MOUSEBioGRID19423573 details
KCMA1_MOUSEMGST1_MOUSEBioGRID19423573 details
KCMA1_MOUSESIA8B_MOUSEBioGRID20114047 details
KCMA1_MOUSENEB2_MOUSEBioGRID28634551 details