Entity Details

Primary name FBLN1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ08879
EntryNameFBLN1_MOUSE
FullNameFibulin-1
TaxID10090
Evidenceevidence at protein level
Length705
SequenceStatuscomplete
DateCreated1994-10-01
DateModified2021-06-02

Ontological Relatives

GenesFbln1

GO terms

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GOName
GO:0001933 negative regulation of protein phosphorylation
GO:0001968 fibronectin binding
GO:0005178 integrin binding
GO:0005201 extracellular matrix structural constituent
GO:0005509 calcium ion binding
GO:0005604 basement membrane
GO:0005615 extracellular space
GO:0007162 negative regulation of cell adhesion
GO:0007566 embryo implantation
GO:0008022 protein C-terminus binding
GO:0010628 positive regulation of gene expression
GO:0016504 peptidase activator activity
GO:0030198 extracellular matrix organization
GO:0031012 extracellular matrix
GO:0042802 identical protein binding
GO:0044877 protein-containing complex binding
GO:0048146 positive regulation of fibroblast proliferation
GO:0062023 collagen-containing extracellular matrix
GO:0070051 fibrinogen binding
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0071635 negative regulation of transforming growth factor beta production
GO:0071953 elastic fiber
GO:0072378 blood coagulation, fibrin clot formation
GO:1900025 negative regulation of substrate adhesion-dependent cell spreading
GO:1904188 negative regulation of transformation of host cell by virus
GO:1904237 positive regulation of substrate-dependent cell migration, cell attachment to substrate
GO:2000146 negative regulation of cell motility
GO:2000647 negative regulation of stem cell proliferation

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000020 Anaphylatoxin/fibulinDomainDomain
IPR000152 EGF-type aspartate/asparagine hydroxylation sitePTMPTM
IPR000742 EGF-like domainDomainDomain
IPR001881 EGF-like calcium-binding domainDomainDomain
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR017048 Fibulin-1FamilyFamily
IPR018097 EGF-like calcium-binding, conserved siteSiteConserved site
IPR026823 Complement Clr-like EGF domainDomainDomain

Diseases

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Interactions

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