Entity Details

Primary name NCF1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ09014
EntryNameNCF1_MOUSE
FullNameNeutrophil cytosol factor 1
TaxID10090
Evidenceevidence at protein level
Length390
SequenceStatuscomplete
DateCreated1995-11-01
DateModified2021-06-02

Ontological Relatives

GenesNcf1

GO terms

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GOName
GO:0001878 response to yeast
GO:0001909 leukocyte mediated cytotoxicity
GO:0002679 respiratory burst involved in defense response
GO:0005737 cytoplasm
GO:0005791 rough endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006612 protein targeting to membrane
GO:0006691 leukotriene metabolic process
GO:0006742 NADP catabolic process
GO:0006801 superoxide metabolic process
GO:0006915 apoptotic process
GO:0006954 inflammatory response
GO:0006968 cellular defense response
GO:0008283 cell population proliferation
GO:0009617 response to bacterium
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016020 membrane
GO:0016175 superoxide-generating NAD(P)H oxidase activity
GO:0016176 superoxide-generating NADPH oxidase activator activity
GO:0017124 SH3 domain binding
GO:0019898 extrinsic component of membrane
GO:0030425 dendrite
GO:0034614 cellular response to reactive oxygen species
GO:0035091 phosphatidylinositol binding
GO:0042554 superoxide anion generation
GO:0042742 defense response to bacterium
GO:0043020 NADPH oxidase complex
GO:0043025 neuronal cell body
GO:0043325 phosphatidylinositol-3,4-bisphosphate binding
GO:0045730 respiratory burst
GO:0045741 positive regulation of epidermal growth factor-activated receptor activity
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046330 positive regulation of JNK cascade
GO:0050665 hydrogen peroxide biosynthetic process
GO:0050830 defense response to Gram-positive bacterium
GO:0050832 defense response to fungus
GO:0060090 molecular adaptor activity
GO:0070946 neutrophil-mediated killing of gram-positive bacterium
GO:0070947 neutrophil-mediated killing of fungus
GO:0071276 cellular response to cadmium ion
GO:1900745 positive regulation of p38MAPK cascade

Subcellular Location

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Subcellular Location
Cytoplasm
Membrane

Domains

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DomainNameCategoryType
IPR001452 SH3 domainDomainDomain
IPR001655 Neutrophil cytosol factor 1FamilyFamily
IPR001683 Phox homologyDomainDomain
IPR015039 NADPH oxidase subunit p47Phox, C-terminalDomainDomain
IPR032136 Neutrophil cytosol factor 1, C-terminalDomainDomain
IPR034909 Neutrophil cytosol factor 1, PX domainDomainDomain
IPR035756 Neutrophil cytosol factor 1, first SH3 domainDomainDomain
IPR035757 Neutrophil cytosol factor 1, second SH3 domainDomainDomain
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR036871 PX domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

4 interactions