Entity Details

Primary name HIF3A_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ0VBL6
EntryNameHIF3A_MOUSE
FullNameHypoxia-inducible factor 3-alpha
TaxID10090
Evidenceevidence at protein level
Length662
SequenceStatuscomplete
DateCreated2007-04-17
DateModified2021-06-02

Ontological Relatives

GenesHif3a

GO terms

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GOName
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001525 angiogenesis
GO:0001666 response to hypoxia
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006366 transcription by RNA polymerase II
GO:0006915 apoptotic process
GO:0016607 nuclear speck
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046983 protein dimerization activity
GO:0071456 cellular response to hypoxia

Subcellular Location

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Subcellular Location
Cytoplasm
Mitochondrion
Nucleus
Nucleus speckle

Domains

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DomainNameCategoryType
IPR000014 PAS domainDomainDomain
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domainDomainDomain
IPR013655 PAS fold-3DomainDomain
IPR013767 PAS foldDomainDomain
IPR021537 Hypoxia-inducible factor, alpha subunitFamilyFamily
IPR035965 PAS domain superfamilyFamilyHomologous superfamily
IPR036638 Helix-loop-helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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