Entity Details

Primary name NLRC5_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionC3VPR6
EntryNameNLRC5_MOUSE
FullNameProtein NLRC5
TaxID10090
Evidenceevidence at protein level
Length1915
SequenceStatuscomplete
DateCreated2010-10-05
DateModified2021-06-02

Ontological Relatives

GenesNlrc5

GO terms

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GOName
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0009617 response to bacterium
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0035556 intracellular signal transduction
GO:0043549 regulation of kinase activity
GO:0045087 innate immune response
GO:0045345 positive regulation of MHC class I biosynthetic process
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0051607 defense response to virus
GO:0060335 positive regulation of interferon-gamma-mediated signaling pathway
GO:0060339 negative regulation of type I interferon-mediated signaling pathway
GO:0060340 positive regulation of type I interferon-mediated signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR001611 Leucine-rich repeatRepeatRepeat
IPR003591 Leucine-rich repeat, typical subtypeRepeatRepeat
IPR006553 Leucine-rich repeat, cysteine-containing subtypeRepeatRepeat
IPR007111 NACHT nucleoside triphosphataseDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily
IPR041210 NLRC5, atypical caspase recruitment domainDomainDomain
IPR041267 NACHT, LRR and PYD domains-containing protein, helical domain HD2DomainDomain

Diseases

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Interactions

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