Entity Details

Primary name EDEM3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ2HXL6
EntryNameEDEM3_MOUSE
FullNameER degradation-enhancing alpha-mannosidase-like protein 3
TaxID10090
Evidenceevidence at protein level
Length931
SequenceStatuscomplete
DateCreated2008-02-05
DateModified2021-06-02

Ontological Relatives

GenesEdem3

GO terms

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GOName
GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
GO:0005509 calcium ion binding
GO:0005788 endoplasmic reticulum lumen
GO:0005975 carbohydrate metabolic process
GO:0006486 protein glycosylation
GO:0006516 glycoprotein catabolic process
GO:0006986 response to unfolded protein
GO:0016020 membrane
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0044322 endoplasmic reticulum quality control compartment
GO:1904380 endoplasmic reticulum mannose trimming
GO:1904382 mannose trimming involved in glycoprotein ERAD pathway

Subcellular Location

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Subcellular Location
Endoplasmic reticulum lumen

Domains

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DomainNameCategoryType
IPR001382 Glycoside hydrolase family 47FamilyFamily
IPR003137 PA domainDomainDomain
IPR012341 Six-hairpin glycosidase-like superfamilyFamilyHomologous superfamily
IPR036026 Seven-hairpin glycosidasesFamilyHomologous superfamily
IPR037322 EDEM3, PA domainDomainDomain
IPR044674 ER degradation-enhancing alpha-mannosidase-like protein 1/2/3FamilyFamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
EDEM3_MOUSEDJC10_HUMANIntAct22665516 details