Entity Details

Primary name NLR1A_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ2LKU9
EntryNameNLR1A_MOUSE
FullNameNACHT, LRR and PYD domains-containing protein 1a
TaxID10090
Evidenceevidence at protein level
Length1182
SequenceStatuscomplete
DateCreated2015-12-09
DateModified2021-06-02

Ontological Relatives

GenesNlrp1a

GO terms

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GOName
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006954 inflammatory response
GO:0019899 enzyme binding
GO:0032495 response to muramyl dipeptide
GO:0032731 positive regulation of interleukin-1 beta production
GO:0032991 protein-containing complex
GO:0042742 defense response to bacterium
GO:0042981 regulation of apoptotic process
GO:0043025 neuronal cell body
GO:0045087 innate immune response
GO:0051402 neuron apoptotic process
GO:0061702 inflammasome complex
GO:0097110 scaffold protein binding
GO:0097300 programmed necrotic cell death

Subcellular Location

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Subcellular Location
Cytoplasm
Inflammasome
Nucleus

Domains

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DomainNameCategoryType
IPR001315 CARD domainDomainDomain
IPR001611 Leucine-rich repeatRepeatRepeat
IPR007111 NACHT nucleoside triphosphataseDomainDomain
IPR011029 Death-like domain superfamilyFamilyHomologous superfamily
IPR025307 FIIND domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily
IPR033516 CARD8/ASC/NALP1, CARD domainDomainDomain
IPR041075 NOD2, winged helix domainDomainDomain
IPR041267 NACHT, LRR and PYD domains-containing protein, helical domain HD2DomainDomain

Diseases

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Interactions

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