Entity Details

Primary name PREX2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ3LAC4
EntryNamePREX2_MOUSE
FullNamePhosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein
TaxID10090
Evidenceevidence at protein level
Length1598
SequenceStatuscomplete
DateCreated2007-05-15
DateModified2021-06-02

Ontological Relatives

GenesPrex2

GO terms

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GOName
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005096 GTPase activator activity
GO:0005886 plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0008344 adult locomotory behavior
GO:0014065 phosphatidylinositol 3-kinase signaling
GO:0048813 dendrite morphogenesis

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000219 Dbl homology (DH) domainDomainDomain
IPR000591 DEP domainDomainDomain
IPR001331 Guanine-nucleotide dissociation stimulator, CDC24, conserved siteSiteConserved site
IPR001478 PDZ domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR035899 Dbl homology (DH) domain superfamilyFamilyHomologous superfamily
IPR036034 PDZ superfamilyFamilyHomologous superfamily
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily
IPR037367 PREX2, DEP domain 1DomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PREX2_MOUSEGNMT_MOUSEBioGRID28205209 details