Entity Details

Primary name STING_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ3TBT3
EntryNameSTING_MOUSE
FullNameStimulator of interferon genes protein
TaxID10090
Evidenceevidence at protein level
Length378
SequenceStatuscomplete
DateCreated2007-01-09
DateModified2021-06-02

Ontological Relatives

GenesSting1

GO terms

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GOName
GO:0000045 autophagosome assembly
GO:0000421 autophagosome membrane
GO:0002218 activation of innate immune response
GO:0002230 positive regulation of defense response to virus by host
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005741 mitochondrial outer membrane
GO:0005768 endosome
GO:0005776 autophagosome
GO:0005777 peroxisome
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0008134 transcription factor binding
GO:0010468 regulation of gene expression
GO:0016239 positive regulation of macroautophagy
GO:0019901 protein kinase binding
GO:0030176 integral component of endoplasmic reticulum membrane
GO:0031323 regulation of cellular metabolic process
GO:0031625 ubiquitin protein ligase binding
GO:0032092 positive regulation of protein binding
GO:0032481 positive regulation of type I interferon production
GO:0032728 positive regulation of interferon-beta production
GO:0035438 cyclic-di-GMP binding
GO:0035458 cellular response to interferon-beta
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0045087 innate immune response
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048471 perinuclear region of cytoplasm
GO:0050727 regulation of inflammatory response
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051259 protein complex oligomerization
GO:0051607 defense response to virus
GO:0061507 cyclic-GMP-AMP binding
GO:0061709 reticulophagy
GO:0071360 cellular response to exogenous dsRNA
GO:0071407 cellular response to organic cyclic compound
GO:1990701 integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Cytoplasmic vesicle
Endoplasmic reticulum membrane
Endoplasmic reticulum-Golgi intermediate compartment membrane
Mitochondrion outer membrane

Domains

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DomainNameCategoryType
IPR029158 Stimulator of interferon genes proteinFamilyFamily
IPR033952 Stimulator of interferon genes protein, C-terminalDomainDomain
IPR038623 Stimulator of interferon genes protein, C-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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