Entity Details

Primary name SPP2B_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ3TD49
EntryNameSPP2B_MOUSE
FullNameSignal peptide peptidase-like 2B
TaxID10090
Evidenceevidence at protein level
Length578
SequenceStatuscomplete
DateCreated2006-05-16
DateModified2021-06-02

Ontological Relatives

GenesSppl2b

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0005654 nucleoplasm
GO:0005765 lysosomal membrane
GO:0005813 centrosome
GO:0005886 plasma membrane
GO:0006509 membrane protein ectodomain proteolysis
GO:0010008 endosome membrane
GO:0015629 actin cytoskeleton
GO:0016020 membrane
GO:0030660 Golgi-associated vesicle membrane
GO:0031293 membrane protein intracellular domain proteolysis
GO:0033619 membrane protein proteolysis
GO:0042500 aspartic endopeptidase activity, intramembrane cleaving
GO:0042803 protein homodimerization activity
GO:0050776 regulation of immune response
GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane
GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane

Subcellular Location

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Subcellular Location
Cell membrane
Endosome membrane
Golgi apparatus membrane
Lysosome membrane
Membrane

Domains

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DomainNameCategoryType
IPR003137 PA domainDomainDomain
IPR006639 Presenilin/signal peptide peptidaseFamilyFamily
IPR007369 Peptidase A22B, signal peptide peptidaseFamilyFamily
IPR033149 Signal peptidase peptidase-like 2BFamilyFamily

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink