Entity Details

Primary name CUL4B_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionA2A432
EntryNameCUL4B_MOUSE
FullNameCullin-4B
TaxID10090
Evidenceevidence at protein level
Length970
SequenceStatuscomplete
DateCreated2010-06-15
DateModified2021-06-02

Ontological Relatives

GenesCul4b

GO terms

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GOName
GO:0004842 ubiquitin-protein transferase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006974 cellular response to DNA damage stimulus
GO:0007049 cell cycle
GO:0010498 proteasomal protein catabolic process
GO:0016567 protein ubiquitination
GO:0019005 SCF ubiquitin ligase complex
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031175 neuron projection development
GO:0031461 cullin-RING ubiquitin ligase complex
GO:0031465 Cul4B-RING E3 ubiquitin ligase complex
GO:0031625 ubiquitin protein ligase binding
GO:0035518 histone H2A monoubiquitination
GO:0042254 ribosome biogenesis
GO:0045732 positive regulation of protein catabolic process
GO:0070914 UV-damage excision repair
GO:0080008 Cul4-RING E3 ubiquitin ligase complex
GO:1900087 positive regulation of G1/S transition of mitotic cell cycle

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001373 Cullin, N-terminalDomainDomain
IPR016157 Cullin, conserved siteSiteConserved site
IPR016158 Cullin homology domainDomainDomain
IPR016159 Cullin repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR019559 Cullin protein, neddylation domainDomainDomain
IPR033044 Cullin-4BFamilyFamily
IPR036317 Cullin homology domain superfamilyFamilyHomologous superfamily
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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