Entity Details

Primary name METK2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ3THS6
EntryNameMETK2_MOUSE
FullNameS-adenosylmethionine synthase isoform type-2
TaxID10090
Evidenceevidence at protein level
Length395
SequenceStatuscomplete
DateCreated2006-01-24
DateModified2021-06-02

Ontological Relatives

GenesMat2a

GO terms

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GOName
GO:0004478 methionine adenosyltransferase activity
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0006556 S-adenosylmethionine biosynthetic process
GO:0006730 one-carbon metabolic process
GO:0007623 circadian rhythm
GO:0009725 response to hormone
GO:0016597 amino acid binding
GO:0034214 protein hexamerization
GO:0042493 response to drug
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0048269 methionine adenosyltransferase complex
GO:0051291 protein heterooligomerization
GO:0051591 response to cAMP
GO:1990830 cellular response to leukemia inhibitory factor

Subcellular Location

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Domains

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DomainNameCategoryType
IPR002133 S-adenosylmethionine synthetaseFamilyFamily
IPR022628 S-adenosylmethionine synthetase, N-terminalDomainDomain
IPR022629 S-adenosylmethionine synthetase, central domainDomainDomain
IPR022630 S-adenosylmethionine synthetase, C-terminalDomainDomain
IPR022631 S-adenosylmethionine synthetase, conserved siteSiteConserved site
IPR022636 S-adenosylmethionine synthetase superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
METK2_MOUSEITA5_MOUSEBioGRID30333137 details
METK2_MOUSESUV91_MOUSEBioGRID23539621 details