Entity Details

Primary name HACE1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ3U0D9
EntryNameHACE1_MOUSE
FullNameE3 ubiquitin-protein ligase HACE1
TaxID10090
Evidenceevidence at protein level
Length909
SequenceStatuscomplete
DateCreated2007-03-20
DateModified2021-06-02

Ontological Relatives

GenesHace1

GO terms

Show/Hide Table
GOName
GO:0000139 Golgi membrane
GO:0000209 protein polyubiquitination
GO:0004842 ubiquitin-protein transferase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0007030 Golgi organization
GO:0007049 cell cycle
GO:0016567 protein ubiquitination
GO:0016604 nuclear body
GO:0030334 regulation of cell migration
GO:0031267 small GTPase binding
GO:0032580 Golgi cisterna membrane
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045732 positive regulation of protein catabolic process
GO:0061025 membrane fusion
GO:0061630 ubiquitin protein ligase activity
GO:0070936 protein K48-linked ubiquitination

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Endoplasmic reticulum
Golgi apparatus

Domains

Show/Hide Table
DomainNameCategoryType
IPR000569 HECT domainDomainDomain
IPR002110 Ankyrin repeatRepeatRepeat
IPR020683 Ankyrin repeat-containing domainDomainDomain
IPR035983 HECT, E3 ligase catalytic domainFamilyHomologous superfamily
IPR036770 Ankyrin repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
HACE1_MOUSEOPTN_MOUSEBioGRID, IntAct25026213 details