Entity Details

Primary name OTUL_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ3UCV8
EntryNameOTUL_MOUSE
FullNameUbiquitin thioesterase otulin
TaxID10090
Evidenceevidence at protein level
Length352
SequenceStatuscomplete
DateCreated2006-11-28
DateModified2021-06-02

Ontological Relatives

GenesOtulin

GO terms

Show/Hide Table
GOName
GO:0002040 sprouting angiogenesis
GO:0004843 thiol-dependent deubiquitinase
GO:0005737 cytoplasm
GO:0008234 cysteine-type peptidase activity
GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway
GO:0016055 Wnt signaling pathway
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0045087 innate immune response
GO:0050728 negative regulation of inflammatory response
GO:0060828 regulation of canonical Wnt signaling pathway
GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:1990108 protein linear deubiquitination

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR023235 FAM105FamilyFamily
IPR023237 Ubiquitin thioesterase otulinFamilyFamily
IPR042467 Peptidase C65, otubain, subdomain 2FamilyHomologous superfamily
IPR042468 Peptidase C65, otubain, subdomain 1FamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
OTUL_MOUSERNF31_MOUSEBioGRID24461064 32325033 details
OTUL_MOUSEUBC_MOUSEBioGRID28190767 details