Entity Details

Primary name KMT2E_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ3UG20
EntryNameKMT2E_MOUSE
FullNameInactive histone-lysine N-methyltransferase 2E
TaxID10090
Evidenceevidence at protein level
Length1868
SequenceStatuscomplete
DateCreated2008-06-10
DateModified2021-06-02

Ontological Relatives

GenesKmt2e

GO terms

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GOName
GO:0000785 chromatin
GO:0002446 neutrophil mediated immunity
GO:0003713 transcription coactivator activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005815 microtubule organizing center
GO:0006306 DNA methylation
GO:0016604 nuclear body
GO:0016607 nuclear speck
GO:0019899 enzyme binding
GO:0030218 erythrocyte differentiation
GO:0032991 protein-containing complex
GO:0035064 methylated histone binding
GO:0035327 transcriptionally active chromatin
GO:0042119 neutrophil activation
GO:0042800 histone methyltransferase activity (H3-K4 specific)
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046872 metal ion binding
GO:0048384 retinoic acid receptor signaling pathway
GO:1900087 positive regulation of G1/S transition of mitotic cell cycle
GO:1905437 positive regulation of histone H3-K4 trimethylation

Subcellular Location

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Subcellular Location
Chromosome
Cytoplasm
Nucleus speckle

Domains

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DomainNameCategoryType
IPR001214 SET domainDomainDomain
IPR001965 Zinc finger, PHD-typeDomainDomain
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR019786 Zinc finger, PHD-type, conserved siteSiteConserved site
IPR019787 Zinc finger, PHD-fingerDomainDomain
IPR037955 Inactive histone-lysine N-methyltransferase 2EFamilyFamily
IPR044434 KMT2E, SET domainDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
KMT2E_MOUSESF01_HUMANIntAct26420826 details
KMT2E_MOUSEP53_MOUSEBioGRID21423215 details