Entity Details

Primary name LRRK1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ3UHC2
EntryNameLRRK1_MOUSE
FullNameLeucine-rich repeat serine/threonine-protein kinase 1
TaxID10090
Evidenceevidence at protein level
Length2014
SequenceStatuscomplete
DateCreated2006-05-02
DateModified2021-06-02

Ontological Relatives

GenesLrrk1

GO terms

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GOName
GO:0004672 protein kinase activity
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0007165 signal transduction
GO:0036035 osteoclast development
GO:0042802 identical protein binding
GO:0045453 bone resorption
GO:0046872 metal ion binding
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1902533 positive regulation of intracellular signal transduction

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR001611 Leucine-rich repeatRepeatRepeat
IPR002110 Ankyrin repeatRepeatRepeat
IPR003591 Leucine-rich repeat, typical subtypeRepeatRepeat
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR011044 Quinoprotein amine dehydrogenase, beta chain-likeFamilyHomologous superfamily
IPR020683 Ankyrin repeat-containing domainDomainDomain
IPR020859 Roc domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR032171 C-terminal of Roc (COR) domainDomainDomain
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily
IPR036770 Ankyrin repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink