Entity Details

Primary name AGAP2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ3UHD9
EntryNameAGAP2_MOUSE
FullNameArf-GAP with GTPase, ANK repeat and PH domain-containing protein 2
TaxID10090
Evidenceevidence at protein level
Length1186
SequenceStatuscomplete
DateCreated2006-05-16
DateModified2021-06-02

Ontological Relatives

GenesAgap2

GO terms

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GOName
GO:0003924 GTPase activity
GO:0005096 GTPase activator activity
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005829 cytosol
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016197 endosomal transport
GO:0019901 protein kinase binding
GO:0030036 actin cytoskeleton organization
GO:0030295 protein kinase activator activity
GO:0033601 positive regulation of mammary gland epithelial cell proliferation
GO:0035014 phosphatidylinositol 3-kinase regulator activity
GO:0042177 negative regulation of protein catabolic process
GO:0043066 negative regulation of apoptotic process
GO:0043524 negative regulation of neuron apoptotic process
GO:0045860 positive regulation of protein kinase activity
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT
GO:0046872 metal ion binding
GO:0060749 mammary gland alveolus development
GO:0090543 Flemming body
GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001164 Arf GTPase activating proteinDomainDomain
IPR001806 Small GTPaseFamilyFamily
IPR001849 Pleckstrin homology domainDomainDomain
IPR002110 Ankyrin repeatRepeatRepeat
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR020683 Ankyrin repeat-containing domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036770 Ankyrin repeat-containing domain superfamilyFamilyHomologous superfamily
IPR037278 ARFGAP/RecO-like zinc fingerFamilyHomologous superfamily
IPR038508 ArfGAP domain superfamilyFamilyHomologous superfamily

Diseases

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