Entity Details

Primary name NDST1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ3UHN9
EntryNameNDST1_MOUSE
FullNameBifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1
TaxID10090
Evidenceevidence at protein level
Length882
SequenceStatuscomplete
DateCreated2006-03-07
DateModified2021-06-02

Ontological Relatives

GenesNdst1

GO terms

Show/Hide Table
GOName
GO:0000139 Golgi membrane
GO:0000271 polysaccharide biosynthetic process
GO:0003279 cardiac septum development
GO:0005794 Golgi apparatus
GO:0006476 protein deacetylation
GO:0006477 protein sulfation
GO:0006954 inflammatory response
GO:0007507 heart development
GO:0007585 respiratory gaseous exchange by respiratory system
GO:0008146 sulfotransferase activity
GO:0008283 cell population proliferation
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0009887 animal organ morphogenesis
GO:0015012 heparan sulfate proteoglycan biosynthetic process
GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity
GO:0016021 integral component of membrane
GO:0019213 deacetylase activity
GO:0030203 glycosaminoglycan metabolic process
GO:0030210 heparin biosynthetic process
GO:0030900 forebrain development
GO:0030901 midbrain development
GO:0035904 aorta development
GO:0043410 positive regulation of MAPK cascade
GO:0045880 positive regulation of smoothened signaling pathway
GO:0048702 embryonic neurocranium morphogenesis
GO:0048703 embryonic viscerocranium morphogenesis
GO:0060976 coronary vasculature development
GO:0102140 heparan sulfate N-deacetylase activity

Subcellular Location

Show/Hide Table
Subcellular Location
Golgi apparatus membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR000863 Sulfotransferase domainDomainDomain
IPR021930 Heparan sulphate-N-deacetylaseDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR037359 Heparan sulfate sulfotransferaseFamilyFamily

Diseases

Show/Hide Table

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
NDST1_MOUSEEXT2_MOUSEDIP18337501 details