Entity Details

Primary name DTX3L_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ3UIR3
EntryNameDTX3L_MOUSE
FullNameE3 ubiquitin-protein ligase DTX3L
TaxID10090
Evidenceevidence at protein level
Length748
SequenceStatuscomplete
DateCreated2009-12-15
DateModified2021-06-02

Ontological Relatives

GenesDtx3l

GO terms

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GOName
GO:0004857 enzyme inhibitor activity
GO:0005634 nucleus
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0006974 cellular response to DNA damage stimulus
GO:0010390 histone monoubiquitination
GO:0016567 protein ubiquitination
GO:0031901 early endosome membrane
GO:0033523 histone H2B ubiquitination
GO:0045087 innate immune response
GO:0061630 ubiquitin protein ligase activity
GO:0070936 protein K48-linked ubiquitination
GO:0097677 STAT family protein binding
GO:1901666 positive regulation of NAD+ ADP-ribosyltransferase activity
GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006302 double-strand break repair
GO:0007219 Notch signaling pathway
GO:0015031 protein transport
GO:0019899 enzyme binding
GO:0035563 positive regulation of chromatin binding
GO:0051607 defense response to virus
GO:0005829 cytosol
GO:0008047 enzyme activator activity
GO:0032991 protein-containing complex
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046872 metal ion binding
GO:0051444 negative regulation of ubiquitin-protein transferase activity
GO:1900182 positive regulation of protein localization to nucleus
GO:1902966 positive regulation of protein localization to early endosome
GO:0002230 positive regulation of defense response to virus by host
GO:0004842 ubiquitin-protein transferase activity
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0008333 endosome to lysosome transport
GO:0032092 positive regulation of protein binding
GO:0033522 histone H2A ubiquitination
GO:0042393 histone binding
GO:0044389 ubiquitin-like protein ligase binding
GO:0051865 protein autoubiquitination
GO:2000646 positive regulation of receptor catabolic process

Subcellular Location

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Subcellular Location
Cytoplasm
Early endosome membrane
Lysosome membrane
Nucleus

Domains

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DomainNameCategoryType
IPR001841 Zinc finger, RING-typeDomainDomain
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR017907 Zinc finger, RING-type, conserved siteSiteConserved site
IPR039396 Deltex, C-terminalDomainDomain
IPR039398 Deltex familyFamilyFamily
IPR039399 Deltex, C-terminal domain superfamilyFamilyHomologous superfamily
IPR042843 DTX3L, RING-HC fingerDomainDomain

Diseases

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Interactions

0 interactions

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