Entity Details

Primary name SMCR8_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ3UMB5
EntryNameSMCR8_MOUSE
FullNameGuanine nucleotide exchange protein SMCR8
TaxID10090
Evidenceevidence at protein level
Length935
SequenceStatuscomplete
DateCreated2007-05-15
DateModified2021-06-02

Ontological Relatives

GenesSmcr8

GO terms

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GOName
GO:0000785 chromatin
GO:0004860 protein kinase inhibitor activity
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006469 negative regulation of protein kinase activity
GO:0006914 autophagy
GO:0010506 regulation of autophagy
GO:0010629 negative regulation of gene expression
GO:0016242 negative regulation of macroautophagy
GO:0019901 protein kinase binding
GO:0032008 positive regulation of TOR signaling
GO:0032045 guanyl-nucleotide exchange factor complex
GO:1901098 positive regulation of autophagosome maturation
GO:1902902 negative regulation of autophagosome assembly
GO:1903432 regulation of TORC1 signaling
GO:1990316 Atg1/ULK1 kinase complex

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR037520 Folliculin/SMCR8, longin domainDomainDomain
IPR037521 Folliculin/SMCR8, tripartite DENN domainDomainDomain

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink